细胞凋亡信号传导通路的研究进展  

Recent Advances on the Signal Transduction Pathways of Apoptosis

作　　者：王力俭[1] 田可川[2] 吴伟伟[2] 徐新明[2] 张廷虎[2] 张艳花[2] 哈尼克孜[2] 

机构地区：[1]新疆畜牧科学院,新疆乌鲁木齐830000 [2]新疆畜牧科学院畜牧所,新疆乌鲁木齐830000

出　　处：《中国畜牧兽医》2011年第10期132-135,共4页China Animal Husbandry & Veterinary Medicine

基　　金：国家绒毛用羊产业技术体系;自治区重大专项(200731132-7)

摘　　要：细胞凋亡是多细胞生物调控生物体的发育、细胞更新和维持内环境稳定的一种重要机制。目前发现细胞凋亡存在死亡受体通路、线粒体通路和内质网通路3条通路,且各通路之间相互联系,共同促进细胞凋亡。作者综述了近年来细胞凋亡信号传导通路及其调控的研究进展。Apoptosis is an important physiological mechanism that organism regulates development of body,cell renewing and maintains homeostasis.In recent years,it was considered that there are three pathways in apoptosis：death receptor pathway,mitochondrion pathway and endoplasmic reticulum pathway which interact with each other and regulate apoptosis coordinately.This author summarized current knowledge of the signal transduction pathways and its regulation in apoptosis.

关 键 词：细胞凋亡 信号传导 死亡受体 线粒体 内质网 

分 类 号：Q257[生物学—细胞生物学]