郴州市2010年手足口病病原学监测分析  

Analysis on Pathogenic Surveillance of Hand-foot-mouth Disease in Chenzhou in 2010

作　　者：郑文[1] 谭徽[1] 刘爱平[1] 谢群[1] 陈白鹭[1] 何清懿[1] 

机构地区：[1]湖南省郴州市疾病预防控制中心,湖南郴州423000

出　　处：《实用预防医学》2011年第10期1977-1978,共2页Practical Preventive Medicine

摘　　要：目的对2010年郴州市手足口病临床诊断病例进行核酸检测,为临床确诊和制定预防控制措施提供依据。方法采用实时荧光RT-PCR法检测临床诊断为手足口病病例的粪便或肛拭子共681份。结果肠道病毒总阳性率为68.9%,EV71阳性率为37.2%,CoxA16阳性率为13.5%。年龄分布主要集中在0-3岁年龄段。性别分布男性明显高于女性。结论郴州市2010年手足口病以EV71为主,占总病例数的53.94%,主要分布在安仁、永兴、宜章、桂阳,重症病例EV71占79.25%。重症手足口病病例主要由EV71引起。Objective To analyze the pathogenic diagnosis of hand-foot-mouth disease in Chenzhou in 2010,and to provide the evidence for clinical diagnosis and making prevention and control measures. Methods A total of 681 stool and anal swab specimens were collected from clinically-diagnosed hand-food-mouth disease patients.The enterovirus was detected by fluorescent RT-PCR with species-special primers. Results The total positive rate of enterovirus was 68.9%.The positive rates of pan-enterovirus,Enterovirus 71 and Coxsackie A16 were 68.9%,37.2% and 13.5%,respectively.High positive rate was found in 0～3 years old children and male patients. Conclusions EV71 was the etiological pathogens of HFMD in Chenzhou in 2010,accounted for 53.94% of the total cases.Severe HFMD cases mostly resulted from EV71.

关 键 词：手足口病 EV71 COXA16 监测 

分 类 号：R512.5[医药卫生—内科学]