重度子痫前期患者子宫胎盘病理学改变与围生儿结局相关性研究  

Study on the correlation between uteroplacental pathological change in patients with severe preeclampsia and perinatal outcome

作　　者：陈宝丽[1] 王燕云[1] 李桂荣[1] 宋海澄[2] 左金玲[3] 

机构地区：[1]河北省唐山市妇幼保健院妇产科,063000 [2]河北联合大学附属开滦医院 [3]河北联合大学

出　　处：《中国妇幼保健》2011年第30期4659-4661,共3页Maternal and Child Health Care of China

基　　金：2009年唐山市科技支撑项目〔09130221a〕

摘　　要：目的:探讨重度子痫前期患者胎盘组织病理学改变对围生儿的影响。方法:选取50例重度子痫前期患者和同期在年龄、孕周匹配且有正常妊娠结局的50例正常对照组产后胎盘组织进行病理检查,对比分析两组胎盘的组织病理学变化。结果:重度子痫前期组与正常对照组相比胎盘梗死灶范围显著增加,差异有统计学意义;早发型重度子痫前期患者胎盘梗死灶范围>30%所占比例较晚发型显著增多,差异有统计学意义(P<0.05)。结论:重度子痫前期患者胎盘梗死灶范围增加,且梗死灶范围对新生儿出生体重有一定影响。Objective：To explore the effect of placental pathological change in patients with severe preeclampsia on perinatal infants. Methods：The placental tissues in 50 cases with severe preeclampsia and 50 women with normal pregnancy outcome in normal control group were selected for pathological examination,the women in the two groups were matched in age and gestational weeks,the placental histopathological changes in the two groups were compared and analyzed. Results：Compared with normal control group,the extent of placental infarction in severe preeclampsia group enlarged obviously,there was significant difference between the two groups;the proportion of placental infarction extent30% in patients with early onset severe preeclampsia was significantly higher than that in patients with late onset severe preeclampsia（P0.05）. Conclusion：The placental infarction extent of patients with severe preeclampsia enlarges,and placental infarction extent has a certain impact on neonatal birth weight.

关 键 词：重度子痫前期 胎盘病理 新生儿出生体重 

分 类 号：R714.245[医药卫生—妇产科学]