补肾活血药辅助CC/HMG/HCG治疗正常促性腺激素性排卵障碍不孕的临床观察  

Clinical observation on reinforcing kidney and activating blood circulation drug and CC/HMG/HCG in treatment of normogonadotrophic ovulatory infertility

作　　者：冯敬华[1] 谈勇[2] 钱云[2] 

机构地区：[1]柳州医学高等专科学校护理系,广西柳州545005 [2]南京中医药大学第一附属医院生殖医学科

出　　处：《中国妇幼保健》2011年第30期4728-4731,共4页Maternal and Child Health Care of China

基　　金：江苏省自然科学基金资助项目〔20100093〕

摘　　要：目的:观察补肾活血药辅助CC/HMG/HCG治疗正常促性腺激素性排卵障碍不孕的临床疗效。方法:将60例不孕患者随机分为两组,补肾活血药辅助CC/HMG/HCG组(治疗组)31例62个周期和CC/HMG/HCG组(对照组)29例60个周期,观察两种治疗方案的治疗效果及异常反应。结果:两组平均促排卵天数、卵泡直径、子宫内膜厚度方面比较差异无统计学意义(P>0.05),治疗组HMG的用量明显低于对照组,差异有统计学意义(P<0.05);治疗组排卵率51.61%,对照组排卵率56.67%,两组比较差异无统计学意义(P>0.05);两组LUFS、OHSS倾向的发生率比较差异无统计学意义(P>0.05);治疗组临床妊娠率51.61%,对照组临床妊娠率24.14%,差异有统计学意义(P<0.05)。结论:补肾活血药辅助CC/HMG/HCG可减少HMG的用量,提高临床妊娠率,对正常促性腺激素性排卵障碍不孕有较好临床效果。Objective：To observe the curative effect of reinforcing kidney and activating blood circulation drug and CC/HMG/HCG in treatment of normogonadotrophic ovulatory infertility. Methods：60 infertile patients were randomly divided into treatment group（reinforcing kidney and activating blood circulation drug and CC/HMG/HCG group,31 patients,62 cycles） and control group（CC/HMG/HCG group,29 patients,60 cycles）,the curative effects and abnormal reactions in the two groups were observed. Results：There was no significant difference in average ovulation time,average diameter of follicles and the depth of endometrium between the two groups（P0.05）,the dose of HMG in treatment group was significantly lower than that in control group（P0.05）;the ovulation rates in treatment group and control group were 51.61% and 56.67%,respectively,there was no significant difference between the two groups（P0.05）;there was no significant difference in the incidences of LUFS and OHSS between the two groups（P0.05）;the clinical pregnancy rates in treatment group and control group were 51.61% and 24.14%,respectively,there was significant difference between the two groups（P0.05）. Conclusion：Reinforcing kidney and activating blood circulation drug and CC/HMG/HCG can reduce the dose of HMG and increase clinical pregnancy rate,and the method had good clinical effect in treatment of normogonadotrophic ovulatory infertility.

关 键 词：排卵障碍 诱发排卵 CC/HMG/HCG 补肾活血 

分 类 号：R711.6[医药卫生—妇产科学]