桂林西瓜霜对宫颈糜烂VEGFmRNA表达的影响  

Effect of Guilin watermelon frost on the expression of VEGF mRNA in patients with cervical erosion

作　　者：蒋秋燕[1] 张琪[2] 莫海霞[2] 宋金玲[2] 李艳林[2] 唐乾利[2] 

机构地区：[1]广西中医学院第一附属医院,广西南宁530023 [2]广西中医学院,广西南宁530023

出　　处：《中国妇幼保健》2011年第30期4776-4777,共2页Maternal and Child Health Care of China

基　　金：2009年国家自然科学基金〔30960482〕;2010年广西自然科学基金〔2010GXNSFA013207〕

摘　　要：目的:探讨桂林西瓜霜对宫颈糜烂VEGF mRNA的表达。方法:将160例宫颈糜烂患者随机分治疗组(用桂林西瓜霜喷敷)、对照组(用bFGF-胶原蛋白海绵贴敷)。应用RT-PCR检测两组宫颈糜烂组织治疗前、后VEGF mRNA的表达。结果:治疗前组织中VEGF mRNA表达两组相对量分别0.48±0.14、0.51±0.11,组间差异无统计学意义(P>0.05);治疗后两组表达均显著增加,相对表达量分别0.79±0.13、0.75±0.16,两组治疗后表达量与治疗前比较差异有统计学意义(P<0.01),组间差异无统计学意义(P>0.05)。结论:桂林西瓜霜对宫颈糜烂上皮组织VEGF mRNA表达有增强作用。Objective：To explore the effect of Guilin watermelon frost on the expression of vascular endothelial growth factor（VEGF） mRNA in patients with cervical erosion. Methods：160 patients with cervical erosion were divided into treatment group（treated with Guilin watermelon frost） and control group（treated with bFGF-collagen sponge） randomly.RT-PCR was used to detect the expression levels of VEGF mRNA before and after treatment. Results：Before treatment,the relative values of VEGF mRNA in the two groups were（0.48±0.14） and（0.51±0.11）,respectively,there was no significant difference between the two groups（P0.05）;after treatment,the expressions of VEGF mRNA in the two groups increased significantly,the relative values were（0.79±0.13） and（0.75±0.16）,respectively;in the two groups,there was significant difference in the expression value of VEGF mRNA before and after treatment（P0.01）,but there was no significant difference between the two groups（P0.05）. Conclusion：Guilin watermelon frost can enhance the expression of VEGF mRNA in cervical epithelial tissue.

关 键 词：桂林西瓜霜 宫颈糜烂 血管内皮生长因子 RT-PCR 

分 类 号：R711.32[医药卫生—妇产科学]