糖耐量试验观察冠心病糖代谢异常的临床研究  

Clinical research of glucose metabolism disorders by the glucose tolerance test in patients with coronary heart disease

作　　者：高珍艳[1] 俎德玲[1] 诸葛毅[2] 杨庆业[1] 郑家胜[1] 徐红青[1] 姜志成 

机构地区：[1]浙江省衢州市人民医院心血管内科,浙江衢州324000 [2]浙江衢州职业技术学院医学院,浙江衢州324000 [3]浙江衢州柯城区石梁卫生院,浙江衢州324000

出　　处：《中国卫生检验杂志》2011年第10期2434-2435,2438,共3页Chinese Journal of Health Laboratory Technology

摘　　要：目的:研究糖耐量试验观察冠心病糖代谢异常对冠脉病变程度的影响。方法:随机选择142例进行冠脉造影术的非糖尿病患者,其中70例确诊冠心病为观察组,根据冠脉病变程度再分轻重2组,72例非冠心病患者为对照组,均进行糖耐量试验及糖化血红蛋白测定。结果:冠心病组餐后2 h血糖(9.53±3.24)mmol/L,高于非冠心病组(6.47±1.52)mmol/L,P<0.05;冠脉狭窄程度与餐后2 h血糖之间呈显著性低度正相关(r为0.337,P<0.01)。结论:冠心病患者糖耐量受损明显,糖耐量试验对冠心病糖代谢异常的临床观察具有重要性。Objective：To study the impact of glucose metabolism disorders on coronary pathological severity by the glucose tolerance test in patients with coronary heart disease.Methods： Coronary angiography was carried out in 142 cases of random selected patients undiagnosed diabetic,70 cases of patients with coronary heart disease as observation group subdivided into 2 groups according to degree of coronary pathological severity and 72 cases of patients without coronary heart disease as control group were investigated with glucose tolerance test and glycosylated hemoglobin determination.Results： 2 h postprandial blood glucose level of observation group was higher than the control group（P〈0.05）.There is a low positive correlation（r =0.337,P〈0.01）between the degree of coronary pathological severity and 2-hour postprandial blood glucose levels in patients with coronary heart disease.Conclusion： The fact shows that significant impaired glucose tolerance in patients with coronary artery disease is present.It is important to use glucose tolerance test for observation of glucose metabolism disorders in patients with coronary artery disease.

关 键 词：冠心病 糖耐量试验 糖代谢异常 

分 类 号：R541.4[医药卫生—心血管疾病]