重症监护病房下呼吸道医院感染鲍曼不动杆菌的耐药性分析  

Antibiotic resistance analysis of nosocomial infections with acinetobacter baumannii from lower respiratory tract in ICU

作　　者：吕婉飞[1] 汪丽[1] 陈敏[1] 

机构地区：[1]宁波大学附属医院检验科,浙江宁波315020

出　　处：《中国卫生检验杂志》2011年第10期2553-2554,共2页Chinese Journal of Health Laboratory Technology

摘　　要：目的:调查重症监护病房(ICU)下呼吸道医院感染鲍曼不动杆菌的耐药情况,指导临床医师合理用药。方法:对医院ICU自2009年1月-2010年12月气管插管或气管切开患者下呼吸道分泌物标本做细菌培养,获得鲍曼不动杆菌83株,并进行药敏结果分析。结果:对鲍曼不动杆菌敏感率最高的是阿米卡星(85.5%),其次为米诺环素(71.0%),其他抗菌药物敏感率<50.0%。结论:ICU下呼吸道医院感染的鲍曼不动杆菌耐药现象非常严重,应继续加强对该菌的监测与控制,严防耐药菌株在ICU暴发流行。Objective：To investigate antibiotic resistance in nosocomial infections with Acinetobacter baumannii from lower respiratory tract in the intensive care unit（ICU） and guide clinically rational use of drug.Methods： 83 A.baumannii strains were obtained through bacterial culture of lower respiratory tract secretions from patients during Jan 2009 to Dec 2010,and the results of drug susceptibility was analyzed.Results： The sensitivity rate to amikacin was the highest,reaching 85.5% and followed by minocycline（71.0%）.The other antibiotics were below 50.0% generally.Conclusion： The drug-resistant status in nosocomial infections with A.baumannii from lower respiratory tract in ICU is very serious.We should continue to strengthen the monitoring of the antibiotic resistance and prevent the outbreak of epidemics of drug resistant strains in ICU.

关 键 词：重症监护病房 下呼吸道 医院感染 鲍曼不动杆菌 耐药性 

分 类 号：R378.99[医药卫生—病原生物学]