A facile and general approach for the synthesis of fluorescent silica nanoparticles doped with inert dyes  

作　　者：MU Xue WU ChuanLiu LAI JinPing CHEN JianBin ZHENG JinSheng LI Chong ZHAO YiBing 

机构地区：[1]Department of Chemistry and the Key Laboratory of Analytical Sciences of Xiamen University, College of Chemistry and Chemical Engineering,Xiamen University, Xiamen 361005, China

出　　处：《Chinese Science Bulletin》2011年第31期3242-3246,共5页

基　　金：supported by the National Natural Science Foundation of China (20875079 and 20835005);the Planned Science and Technology Project of Xiamen, China (3502z20080011);the Specialized Research Fund for the Doctoral Program of Higher Education of China (200803840007)

摘　　要：A general and facile approach was developed for the synthesis of almost monodisperse fluorescent silica nanoparticles (NPs) doped with inert dyes, which are organic fluorophores that are strongly fluorescent but are hydrophobic or lack a covalent binding group. The prepared NPs were mesoporous and the dye molecules were encapsulated in the pores via hydrophobic interaction with the CTAB template. The NPs were stable and highly fluorescent in aqueous solution, and have potential applications in bioanalysis and fluorescence encoding.A general and facile approach was developed for the synthesis of almost monodisperse fluorescent silica nanoparticles （NPs） doped with inert dyes, which are organic fluorophores that are strongly fluorescent but are hydrophobic or lack a covalent binding group. The prepared NPs were mesoporous and the dye molecules were encapsulated in the pores via hydrophobic interaction with the CTAB template. The NPs were stable and highly fluorescent in aqueous solution, and have potential applications in bioanalysis and fluorescence encoding.

关 键 词：有机荧光染料 纳米颗粒 惰性 合成 硅胶 轻便 纳米粒子 疏水相互作用 

分 类 号：TB383.1[一般工业技术—材料科学与工程]