菌痢住院患儿耐药性分析与临床用药策略  

作　　者：陆姝[1] 邓元将 魏红[1] 李学娟[1] 

机构地区：[1]深圳市儿童医院西药房,518026

出　　处：《当代医学》2011年第31期49-50,共2页Contemporary Medicine

摘　　要：目的探讨菌痢住院患儿耐药性分析与临床用药策略。方法 2008年2月～2010年7月,儿科共收治160例急性痢疾患儿,通过实验室检查和临床用药进行分析。结果实验室检查送检75例,呈阳性26例,送检阳性率为34.7%,菌株均为志贺菌福氏B群。采用4种类常用抗生素发现氨苄青霉素耐药率100%,但对头孢三代和氨基糖苷类、喹诺酮类具有敏感性。结论采用头孢三代可以治疗菌痢,磷霉素可与环丙沙星联合用药治疗,慎用氨基糖苷类、喹诺酮类抗生素。Objective To investigate the analysis of bacillary dysentery in hospitalized children with clinical drug resistance strategies.Methods One hundred and sixty cases of pediatric acute diarrhea in children from February 2008 to July 2010 in our hospital were treated through laboratory and clinical medicine for analysis.Results In seventy five cases with laboratory submission 26 cases were positive,the positive rate was 34.7%,strains were Shigella flexneri B group.Found with four types of commonly used antibiotics ampicillin resistance rate was 100%,but three generations of cephalosporins and aminoglycosides,quinolones and sensitive.Conclusion The three generations of cephalosporins to treat dysentery,fosfomycin combination therapy with ciprofloxacin,caution aminoglycosides,quinolones.

关 键 词：细菌性痢疾 耐药性 临床用药 

分 类 号：R725.1[医药卫生—儿科]