不同疾病的痰证患者血浆hs-CRP的水平研究  

Study of Level of Plasma High Sensitivity C-Relective Protein in Different Disease

作　　者：张霄霖[1] 何小琦[1] 罗承锋[1] 

机构地区：[1]广州医学院第二附属医院中医科,广州510260

出　　处：《血栓与止血学》2011年第5期221-223,共3页Chinese Journal of Thrombosis and Hemostasis

基　　金：广东省中医药管理局项目(2007142)

摘　　要：目的从糖尿病肾病(DN)及脑梗死(CI)的痰证患者患者血浆hs-CRP的水平探讨痰证的实质,为痰证的辨证提供客观化指标。方法收集临床病例,对糖尿病肾病痰证组及非痰证组,脑梗死痰证组及非痰证组,正常对照组,采用酶联免疫法检测血浆hs-CRP水平。结果脑梗死与糖尿病肾病患者血浆hs-CRP的水平的升高均高于正常对照组(P<0.05),糖尿病肾病患者中痰证组血浆hs-CRP的水平5.89±3.27与非痰证组5.28±2.8无明显变化(P>0.05),而脑梗死患者中痰证组血浆hs-CRP的水平为10.58±6.86高于非痰证组的8.76±4.52(P<0.05)。结论 hs-CRP不能为糖尿病肾病的痰证辨证提供依据,可作为脑梗死痰证的微观辨证依据之一,但并不是所有痰证辨证微观指标。Objective To approach essence of phlegm syndrome through study of level of plasma high sensitivity C-relective protein（hs-CRP） in diabetic nephropathy（DN） and cerebral Infarction（CI）.Methods The case were divided five groups to DN phlegm syndrome group,DN phlegm non-syndrome group,CI phlegm syndrome group,CI phlegm non-syndrome group,normal control group,to detect level of Serum hs-CRP of five groups.Results the level of DN and CI hs-CRP showed significant advance compared with normal control group,there were not marked change in DN phlegm syndrome group compared with DN phlegm non-syndrome group（5.89±3.27 vs 5.28±2.8,P〉0.05）,and level of serum hs-CRP of CI phlegm syndrome group showed significant advance compared with CI phlegm non-syndrome group（10.58±6.86 vs 8.76±4.52,P〈0.05）.Conclusion hs-CRP may be part evidence of microcosmic syndrome differentiation of CI phlegm syndrome,but may be incorrect such as hs-CRP was part evidence all of microcosmic syndrome differentiation of all phlegm syndrome.

关 键 词：痰证 脑梗死 糖尿病肾病 高敏C-反应蛋白 

分 类 号：R256[医药卫生—中医内科学]