西酞普兰加服中药解郁汤治疗老年抑郁症43例临床观察  

Control study on combined treatment of Citalopram and Chinese medicinal herb with senile depression

作　　者：李清亚[1] 王晓慧[1] 刘杰[1] 王瑛[1] 程俊[1] 李晓楠[1] 

机构地区：[1]解放军第261医院国家中医药管理局中西医结合治疗抑郁症重点专病中心,北京海淀100094

出　　处：《中医药导报》2011年第10期15-17,共3页Guiding Journal of Traditional Chinese Medicine and Pharmacy

基　　金：首都医学科技发展基金重点支持类课题(SF-2007-Ⅱ-04)

摘　　要：目的:观察西酞普兰加服中药解郁汤治疗老年抑郁症的临床疗效。方法:将符合标准的86例老年抑郁症患者随机分为治疗组和对照组各43例,分别应用西酞普兰加服自拟中药解郁汤与单纯应用西酞普兰治疗,疗程8周,用汉密顿抑郁量表评定临床疗效。结果:经治疗8周后,治疗组总有效率为90.7%,对照组为76.7%,两组比较,差异有统计学意义(P<0.05),治疗组优于对照组,且治疗组在降低汉密顿抑郁评分均优于对照组(P<0.05)。结论:西酞普兰加服自拟中药解郁汤治疗老年抑郁症的临床效果优于单纯应用西酞普兰。Objective To compare the efficacy of Chinese medicial herb and Citalopram in the treatment of senile depression.Methods.86 patients with depression were randomly assigned to Chinaese medicial herb group and Citalopram group for 8 weeks.The efficacy was evaluated with Hamilton depression scale（HAMD）.Results The total score of HAMD and clinical efficacy in Citalopram group was significantly lower than that in Chinese medicial herb group after 8 weeks.Conclusion The combinative treatment of Chinese medicine herb and Citalopram has a good effect on senile depression.

关 键 词：西酞普兰 解郁汤 老年抑郁症 

分 类 号：R256.2[医药卫生—中医内科学]