瑞芬太尼复合咪唑安定辅助臂丛神经阻滞麻醉的临床应用  

Clinical application of remifentanil and midazolam assisted anesthesia of brachial plexus nerve block

作　　者：王遂之[1] 蒋民霞[1] 李莺英[1] 刘贤琼[1] 

机构地区：[1]江西省吉安市中心人民医院麻醉科,江西吉安343000

出　　处：《中国当代医药》2011年第28期74-75,共2页China Modern Medicine

摘　　要：目的:评价瑞芬太尼复合咪唑安定辅助臂丛神经阻滞的麻醉效果及安全性。方法:将60例上肢手术行臂丛神经阻滞患者随机均分成观察组和对照组,观察组应用瑞芬太尼复合咪唑安定麻醉,对照组应用芬太尼复合氟哌利多麻醉,观察并记录患者围麻醉期血流动力学和呼吸参数[心率(HR)、平均动脉压(MAP)、脉搏氧饱和度(SpO2)]的变化,术中麻醉镇痛效果及不自主体动的发生率,记录术毕时嗜睡及顺行性遗忘情况。结果:两组患者围麻醉期血流动力学和呼吸参数(HR、MAP、SpO2)变化差异无统计学意义(P>0.05),观察组麻醉镇痛效果及顺行性遗忘效果优于对照组(P<0.05),术中不自主体动及术毕时嗜睡发生率显著低于对照组(P<0.05)。结论:瑞芬太尼复合咪唑安定用于臂丛神经阻滞具有良好的镇痛及顺行性遗忘作用,并且减少了术中不自主体动及术毕时嗜睡的发生。Objective：To observe the effectiveness and safety of remifentanil and midazolam assisted anaesthetizing brachial plexus nerve block.Methods：60 patients with brachial plexus upper extremity surgery were randomly divided into observation group and reference group,the observation group used remifentanil and midazolam and the reference group used fentanyl and droperidol.The changes of hemodynamic and inspiration parameters（HR,MAP,SpO2）,the analgesic effects and not autonomous body motion occurring rate during anesthetic period were observed and noted.Drowsiness after the operation and anterograde amnesia were also recorded.Results：There was no significant difference in the changes of hemodynamic and inspiration parameters between the two groups（P〉0.05）.For the analgesic effects and anterograde amnesia,the observation group was better than the reference group（P〈0.05）.For the occurring rate of not autonomous body motion in operation and drowsiness after the operation,the observation group was obviously less than the reference group（P〈0.05）.Conclusion：Remifentanil and midazolam have good analgesia and anterograde amnesia function for the brachial plexus nerve block.It also reduces the occurring rate of not autonomous body motion in the operation and drowsiness after the operation.

关 键 词：瑞芬太尼 咪唑安定 臂丛神经阻滞 顺行性遗忘 

分 类 号：R614[医药卫生—麻醉学]