模拟失重条件下长时间脑力负荷始末前额区脑电多尺度熵的变化分析  

Changes of EEG Signal Multiscale Entropy at Prefrontal Cortex Area after Mental Workload Operation in Simulated Weightlessness

作　　者：杨辉[1] 韦明[1] 牟锴钰[1] 田甜[2] 高美萍[1] 段玉兴[3] 

机构地区：[1]中国航天员科研训练中心,北京100094 [2]首都师范大学心理系学习与记忆实验室,北京100048 [3]西安卫星测控中心渭南测控站,陕西渭南714000

出　　处：《航天医学与医学工程》2011年第5期369-371,共3页Space Medicine & Medical Engineering

基　　金：中国载人航天工程基金资助

摘　　要：目的观察头低位卧床模拟失重期间脑电信号复杂度的变化,研究脑电信号多尺度熵与脑疲劳的关系。方法 8名健康男性志愿者以-15°头低位卧床(HDBR)为模拟失重,+15°头高位卧床(HUBR)为对照,志愿者静息30 min后进行2 h内容为1-back图片记忆匹配VDT作业。结果实验初HDBR条件下志愿者前额区脑电多尺度熵比HUBR条件下高,两种条件下实验末多尺度熵下降显著,HDBR条件下降幅高于HUBR条件下降幅。结论 1)志愿者短期处于模拟失重条件的应激能力会提高;2)志愿者执行长时间脑负荷任务后短时记忆能力下降,HDBR条件下志愿者执行长时间脑负荷作业更易脑疲劳;3)脑电多尺度熵随脑疲劳程度加深而逐渐降低,可用于脑疲劳的监测。Objective To investigate the relationship between multiscale entropy（MSE）and mental fatigue by analyzing the changes of EEG signal complexity during simulated weightlessness.Methods Eight healthy male subjects performed visual display terminal（VDT）operation task of1-back picture-matching during head-down bed rest（HDBR）as simulated weightlessness and head-up bed rest（HUBR）as control respectively for 2 h.ResultsAt the beginning of the experiment,MSE of EEG signal at prefrontal cortex area was greater in HDBR as compared with that in HUBR.At the end of the experiment,MSE decreased significantly in both conditions.Especially,the amplitude of MSE in HDBR decreased more significantly than that in HUBR.Conclusion1）The irritability is higher when subjects are in short-term simulated weightlessness condition.2）After long-time mental workload task,the short-term memory ability decrease.Compared with in ground condition,subjects obtain mental fatigue more easily in simulated weightlessness condition.3）MSE,which decreases with the increase of mental fatigue level,could be applied to monitoring mental fatigue.

关 键 词：模拟失重 脑疲劳 记忆 多尺度熵 

分 类 号：R857.3[医药卫生—航空、航天与航海医学]