老年患者长期应用阿司匹林的安全性分析  

Elder patients with long-term use of aspirin safety analysis

作　　者：乔森[1] 雷鸣[1] 寇玉红[1] 杨爱民[1] 周蕾[1] 潘晓明[1] 

机构地区：[1]吉林市中心医院,132011

出　　处：《中国实用医药》2011年第27期22-23,共2页China Practical Medicine

摘　　要：目的观察老年心脑血管患者长期应用阿司匹林的安全性。方法 2004年1月至2009年1月,在吉林市中心医院特诊一疗区住院的老年心脑血管患者共232例。对232例分别进行12个月、3年和5年的随访。随访内容包括:阿司匹林的应用情况及有无不良反应。选取的患者在12个月、3年和5年,分别进行头部CT、心电图等检查并测定出血尿常规、凝血时间、肝功能、肾功能。结果随访232例中,209例坚持服用阿司匹林至少12个月,不良反应:消化道反应32例,皮疹0例,轻微出血或发生血小板减少15例,大出血0例,无肝肾功能损害。患者用药依从性达96%。结论老年心脑血管患者长期应用阿司匹林,依从性好,不良反应少,但仍需监测。Objective To observe the eider patients with cardiovascular long-term use of aspirin safety. Methods From January 2004 to January 2009, in Jilin city center, special clinic with 232 eider patients were selected. We follow up these 232 cases separately, in 12 months, 3 years and 5 years. Follow-up content included：the application of aspirin and presence of harmful response. The selection of patients in 12 months, 3 years and five years, respectively, the head CT, electrocardiogram, check out and the determination of urine, and clotting time, liver function and renal function. Results There were 209 cases in 232 cases of the follow- up, adhering to aspirin at least 12 months, adverse reaction：gastrointestinal reaction 32 cases, and rash 0 example, minor bleeding or happen thrombocytopenia in 15 cases, massive hemorrhage 0 example, liver and kid- ney function without damage. Treating patients compliance of 96%. Conclusion Old patients with cardiovascular long-term should use aspirin, compliance, fewer side effects, but the patients still need monitoring.

关 键 词：心脑血管患者 老年 阿司匹林 安全性 

分 类 号：R973.2[医药卫生—药品]