中药炮制辅料甘草汁的质量标准研究  

Study on the Quality Standard of Licorice Juice as A Processing Excipient

作　　者：钮正睿[1] 毛淑杰[1] 顾雪竹[1] 刘洪宇[2] 李先端[1] 

机构地区：[1]中国中医科学院中药研究所,北京100700 [2]国家食品药品监督管理局保健食品审评中心,北京100070

出　　处：《中国实验方剂学杂志》2011年第21期100-104,共5页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：中国中医科学院创新团队项目(ZZ2006096)

摘　　要：目的:制定炮制辅料甘草汁的质量标准,以保证甘草汁和甘草汁所炮制饮片的质量稳定。方法:采用TLC鉴别、常规检测和HPLC测定法进行研究。结果:建立了以甘草酸铵和甘草苷作为对照品的TLC鉴别方法,对甘草汁中灰分、可溶性固形物进行了检测,测定了药汁中甘草酸和甘草苷含量。结论:对炮制辅料中的药汁之一——甘草汁进行了较为系统的质量研究,初步制定其质量标准,方法简便可靠,可以用于甘草汁的质量评价。Objective：To establish the quality standard of licorice juice as a processing excipient.Method： TLC identification,routine testing and determination by HPLC of ten batches of licorice juice were performed.Result： The identification method of licorice juice was established with both ammonium glycyrrhizate and liquiritin as reference substances for the first time.The content data of ash and soluble solid was obtained.The concentration data of glycyrrhizic acid and liquiritin was obtained.Conclusion： For the first time the research on quality standard of licorice juice was conducted systematically and the established standard can be used to control the quality of licorice juice as a processing excipient.

关 键 词：炮制辅料甘草汁 质量标准 薄层色谱 甘草酸 甘草苷 高效液相色谱 

分 类 号：R284.1[医药卫生—中药学]