78例早发型重度子痫前期临床分析  

Clinical analysis of 78 cases of early - onset severe preeclampsia

作　　者：梁志元[1] 杨惠[1] 林萍[1] 

机构地区：[1]徐州市妇幼保健院产科,江苏徐州221009

出　　处：《徐州医学院学报》2011年第7期480-482,共3页Acta Academiae Medicinae Xuzhou

摘　　要：目的探讨早发型重度子痫前期发病孕周与围生期母儿预后的关系。方法对本院产科78例早发型重度子痫前期患者进行临床回顾性分析。根据其发病孕周分成3组，即A组（孕周〈28周）、B组（28周≤孕周〈32周）、C组（32周≤孕周〈34周）。比较分析各组孕妇并发症发生情况以及新生儿窒息率和围生儿病死率。结果3组早发型重度子痫前期患者并发症发生率随发病孕周延长而下降，但3组间差异无统计学意义；3组新生儿窒息率和围生儿病死率均随发病孕周延长而下降，且3组问差异均有统计学意义（P〈0．05）；B组期待治疗时间均明显长于其他2组（P〈0．05），各组患者的分娩方式均以剖宫产为主。结论早发型重度子痫前期严重影响母儿健康，在保守治疗过程中，应严密监护母胎情况，适当延长孕周，适时终止妊娠，提高新生儿存活率。Objective To investigate the effect of gestational age of the onset of early - onset severe preeclampsia on the maternal and neonatal prognosis. Methods A retrospective clinical analysis was conducted on 78 patients with early - onset severe preeelampsia. They were divided into three groups according to pathogenic weeks of gestation ： group A （gestational age 〈 28 weeks）, group B （28 weeks≤gestational age 〈 32 weeks） and group C （32 weeks ≤ gesta- tional age 〈 34 weeks）. The incidence of pregnancy complications in the pregnant women, the neonatal asphyxia rate and perinatal infant mortality rate in each group were compared and analyzed. Results The incidences of pregnancy complications in early - onset severe preeclampsia groups declined with the progression of pathogenic weeks of gestation, while the differences among the three groups had no statistical significance; The neonatal asphyxia rate and perinatal infant mortality rate of the three groups declined along with the progession of pathogenic weeks of gestation, and there were significant statistical differences between the three groups （ P 〈 0.05 ）. Expectant treatment time of group B was significantly longer than that of either of the other two groups （ P 〈 0.05 ）, and Cesarean section was a main method of delivery for all groups. Conclusion The early - onset severe preeelampsia seriously affect the maternal and neonatal health. During the expectant treatment, the maternal and fetal situation should be closely monitored, and the gestational age was appropriately extended. The pregnancy should be terminated at appropriate time to improve neonatal survival rate.

关 键 词：早发型重度子痫前期 并发症 新生儿窒息 围生儿死亡 期待治疗 

分 类 号：R714.246[医药卫生—妇产科学]