CO_2低压溶剂羧化法合成2,6-二羟基苯甲酸工艺研究  

Study on preparation of 2,6-dihydroxybenzoic acid by solvent carboxylation with CO_2 under low pressure

作　　者：唐蓉萍[1] 韩庆荣 

机构地区：[1]兰州石化职业技术学院,甘肃兰州730060 [2]甘肃省化工研究院,甘肃兰州730020

出　　处：《天然气化工—C1化学与化工》2011年第5期53-56,共4页Natural Gas Chemical Industry

摘　　要：研究了间苯二酚低压溶剂羧化法合成2,6-二羟基苯甲酸。适宜的反应条件为:反应压力0.4MPa～0.5MPa反应温度140℃,反应时间6h^7h,n(间苯二酚)/n(氢氧化钾)=1/2.05,溶剂为甲苯。在适宜的条件下,产物经洗涤、酸化、脱色和重结晶等后处理工序,产品收率达70%,纯度大于99%(HPLC)。Preparation of 2,6-dihydoxybenzoic acid by direct carboxylation of resorcinol with CO2 in solvent under low pressure was studied. The optimum reaction parameters were determined as follows： reaction pressure of 0.4-0.5MPa, reaction temperature of 140℃, reaction time of 6-7 hours, molar ratio of resorcinol to potassium hydroxide of 1：2.05 and toluene as solvent. Under the optimized conditions, after washing, acidification, decolorization and reerystallization, the yield of 2,6-dihydroxybenzoic acid could be up to 70% with the purity of more than 99 % （HPLC）.

关 键 词：2  6-二羟基苯甲酸 合成 间苯二酚 二氧化碳 溶剂羧化 低压合成 

分 类 号：TQ21[化学工程—有机化工]