无症状慢性阻塞性肺疾病患者相关特征分析  

STUDY ON CHARACTERISTICS OF THE PATIENTS WITH NON-SYMPTOMATIC CHRONIC OBSTRUCTIVE PULMONARY DISEASE

作　　者：蒋汝刚[1] 范杉[1] 罗德生[2] 黄翠萍[3] 

机构地区：[1]湖北咸宁学院预防医学教研室,咸宁437100 [2]咸宁学院生物化学教研室 [3]咸宁学院内科学教研室

出　　处：《现代预防医学》2011年第21期4341-4343,共3页Modern Preventive Medicine

基　　金：湖北省教育厅科研基金项目(B200628001)

摘　　要：[目的]了解鄂南农村居民无症状慢性阻塞性肺疾病(COPD)患病状况及患者的流行病学特征,为防治COPD提供科学依据。[方法]以多阶段抽样方法,抽取鄂南农村居民1883例进行问诊、体检和肺功能检测,并采用统一的问卷进行调查。[结果]共检出COPD患者186例,总患病率为9.88%,其中无症状者71例,占38.17%;有症状者115例,占61.83%。无症状COPD的患病率为3.77%。无症状组和有症状组患者年龄、性别、职业、受教育程度、行饮情况,使用燃料情况和吸烟史比较,差异均无统计学意义(P﹥0.05)。两组吸烟指数差异有统计学意义(P﹤0.01),肺功能检测显示,有症状组第1s用力呼气容积(FEV1)、第1s用力呼气容积占预计值百分比(FEV1占预计值%)与无症状组比较,差异均有统计学意义(P﹤0.05或P﹤0.01)。[结论]该地区COPD患病率较高,其中无症状COPD的比例也较高。如果单凭症状,易造成COPD的漏诊和对疾病危害的低估。[Objective]To explore the prevalence rate of non-symptomatic chronic obstructive disease and the epidemiological characteristics of patients in rural area in southern part of Hubei province and to provide scientific evidence of prevention and treatment for COPD.[Methods]A multistage survey for 1 883 people in rural in southern part of Hubei province was performed.Information of medical history and symptom were obtained,and physical examinations and lung function tests were conducted for every participant,and made questionnaire investigation into every participant.[Results]The prevalence of COPD was 9.88% in this area.In these patients,71（38.17%）were non-symptomatic and 115（61.83%）were symptomatic,the prevalence of non-symptomatic COPD being 3.77%.There was no statistical difference in the age,sex,occupation,education level,cooking times,the status of using fuel and smoking history between the symptomatic and non-symptomatic groups（P﹥0.05）,there was statistical difference in smoking index between the two groups（P﹤0.01）.The forced expired volume in one second（FEV1）and FEV1% predicted were lower in the symptomatic group than those in the non-symptomatic group（P﹤0.05 or P﹤0.01）.[Conclusion]The prevalence of COPD is high in this area with a high percentage of non-symptomatic patients.The COPD prevalence might be underestimated due to the symptom free patients.

关 键 词：肺疾病 慢性阻塞性 症状 流行病学 

分 类 号：R563[医药卫生—呼吸系统]