甲氨基阿维菌素苯甲酸盐-HTlc杂化物水分散粒剂的优化配方  

Water Dispersible Granule of Emamectin Benzoate-HTlc

作　　者：贾猛猛[1] 李丽芳[2] 金荣荣[2] 徐雪峰[1] 

机构地区：[1]山东农业大学植物保护学院,山东泰安271018 [2]山东农业大学化学与材料科学学院,山东泰安271018

出　　处：《农药》2011年第11期810-812,共3页Agrochemicals

基　　金：山东省优秀中青年科学家科研奖励基金(2008BS07016)

摘　　要：[目的]筛选出26%甲氨基阿维菌素苯甲酸盐-HTlc杂化物水分散粒剂的最佳配方。[方法]通过对润湿剂、分散剂、崩解剂、黏结剂等助剂的筛选,采用正交试验设计的方法确定了最佳配方。[结果]甲氨基阿维菌素苯甲酸盐-HTlc杂化物78%,润湿剂SDS+RS为6%,分散剂Morwet D425为5%,崩解剂尿素为10%,黏结剂蔗糖为1%。[结论]制剂悬浮率90%以上,崩解时间小于180 s,热贮[(54±2)℃,14 d]分解率小于5%,产品各项指标符合水分散粒剂的要求。[Aims] The preparation method of the water dispersible granules of emamectin benzoate-HTlc 26% was introduced. [Methods] The suitable wetting agent, dispersant, disintegrant and binder were selected, the optimum formula was determined using the orthogonal test design. [Results] The new formulation included emamectin benzoate-HTlc, wetting agent SDS＋RS, dispersant Morwet D425, disintegrant urea, binder saccharose in mixture with mass fractions were 78, 6, 5, 10 and 1%. [Conclusions] The experimental results showed that the suspension rate of products was over 90%, the dispersion time was less than 180 seconds and the decomposition rate of its active ingredient was less than 5% at （54±2）℃ with 14 days, which conformed to the requirements of the formulation.

关 键 词：甲氨基阿维菌素苯甲酸盐-HTlc杂化物 水分散粒剂 正交试验设计 

分 类 号：TQ450.6[化学工程—农药化工]