艾灸对兔退变颈椎间盘蛋白多糖含量的影响  

Effect of Moxibustion on the Contents of Proteoglycan of Rabbits with Degeneration of Cervical Intervertebral Disc

作　　者：蔡洁[1] 彭锐[2] 熊勇[2] 

机构地区：[1]广州军区武汉总医院骨科,武汉430070 [2]湖北中医药大学针灸骨伤学院

出　　处：《中国中医骨伤科杂志》2011年第10期10-11,共2页Chinese Journal of Traditional Medical Traumatology & Orthopedics

基　　金：湖北省教育厅科研项目(Q20091604)

摘　　要：目的:观察艾灸对兔退变颈椎间盘蛋白多糖的影响,探讨艾灸防治颈椎间盘退变的作用及可能机制。方法:24只日本大耳白兔随机分为艾灸组、模型组和正常组,每组8只,采用颈屈曲位固定法制备兔颈椎间盘退变模型,造模后立即干预。艾灸组温和灸颈部夹脊穴,每穴15min,1次/d。造模3月后,各组取出退变椎间盘组织,测量其蛋白多糖含量。结果:模型组椎间盘蛋白多糖含量明显减少(P<0.01),艾灸组椎间盘蛋白多糖含量较模型组高(P<0.01),艾灸组和正常组比较差异无统计学意义(P>0.05)。结论:艾灸可防止兔颈椎间盘蛋白多糖含量过度减少,对兔颈椎间盘退变有一定延缓作用。Objective：To observe the effect of moxibustion on the contents of proteoglycan of rabbits with degeneration of cervical intervertebral disc,and to explore its potential mechanism.Methods：Twenty-four Japanese white rabbits were divided into three groups at random： moxibustion group,model group and normal group,8 in each group.Model of degeneration of cervical intervertebral disc was established with modified fixation in sixty-degree flexion,and intervention was used at the beginning of model preparation.Animals in the moxibustion group were treated with moxibustion applied on cervical paravertebral point（EX-B 2）（each acupoint for 15minutes,once a day）;animals in the nomal group with nothing.The intervertebral disc tissues were harvested three months after model preparation,and the proteoglycan contents were measured.Results：The contents of proteoglycan in the model group were significantly decreased（P0.01）.Compared with the model group,the contents of proteoglycan in the moxibustion were higher（P0.01）,but there was no notable difference between the moxibustion group and the normal group（P0.05）.Conclusion： Moxibustion can prevent depression of the contents of proteoglycan,which may contribute to the therapeutic effect of moxibustion on degeneration of cervical intervertebral disc.

关 键 词：艾灸 椎间盘 退变 蛋白多糖 

分 类 号：R245.81[医药卫生—针灸推拿学]