“超声针灸”足三里穴对胃黏膜损伤兔前列腺素E2水平的影响  

Influence of Ultrasound Acupuncture of Zusanli on Prostaglandin E_2 in Alcohol-induced Gastric Mucosal Lesion Rabbits

作　　者：李泞珊[1] 邹建中[1] 丁霞娟[1] 高艳[1] 张璇[1] 熊春艳[1] 赵骏[1] 

机构地区：[1]重庆医科大学生物医学工程系；省部共建超声医学工程国家重点实验室；超声医学工程重庆市市级重点实验室,重庆市400016

出　　处：《中国超声医学杂志》2011年第10期878-881,共4页Chinese Journal of Ultrasound in Medicine

摘　　要：目的探讨"超声针灸"作用于足三里穴治疗胃黏膜损伤的有效性。方法新西兰大白兔32只,随机分为4组,每组8只,分别为超声针灸组、毫针组、模型对照组、空白对照组。用无水乙醇按1 ml/kg灌胃,建立胃黏膜损伤模型。测量各组兔胃液、胃黏膜中前列腺素E_2的含量,并观察其胃黏膜损伤指数。结果兔胃液、胃黏膜中前列腺素E_2的含量,超声针灸组、毫针组均较模型对照组显著提高(P<0.05);超声针灸组与毫针组相比,无显著差异(P>0.05)。兔胃黏膜损伤指数,超声针灸组、毫针组较模型对照组显著降低(P<0.05);超声针灸组与毫针组相比,无显著差异(P>0.05)。结论 "超声针灸"作用于胃黏膜损伤兔的双侧足三里穴,能有效治疗胃黏膜损伤,且可达到与毫针相同的效果。Objective To explore the effectiveness of ultrasound acupuncture for treating the gastric mucosal le- sion rabbits. Methods 32 healthy Zelanian rabbits were divided into 4 groups （n=8） randomly： Ultrasound acupunc- ture, Acupuncture needle, Model control, Blank control. Acute gastric mucosal lesion rabbit model was built by etha- nol ingestion, 1 ml/kg. Detect the prostaglandin E2 level in gastric juice and gastric mucosa tissue and observe the in- dex of gastric mucosa lesion. Results The prostaglandin E2 level of gastric juice and gastric mucosa tissue in Ultra sound acupuncture and Acupuncture needle are observably higher than that of Model group （P〈0.05）, there is no ob- servably difference between Ultrasound acupuncture and Acupuncture needle （P〉0.05）. The index of gastric mucosa lesion in Ultrasound acupuncture and Acupuncture needle are observably lower than that of Model group （P〈0.05）, there is no observably difference between Ultrasound acupuncture and Acupuncture needle （P：〉0.05）. Conclusions Ultrasound acupuncture can effectively cure the rabbits＂ gastric mucosa lesion by irradiating the ＂Zusanli＂ （ST36） of two sides, which can achieve the same effect with the acupuncture needle.

关 键 词：“超声针灸” 胃黏膜损伤 兔 前列腺素E2 

分 类 号：R445.1[医药卫生—影像医学与核医学] R245[医药卫生—诊断学]