磁共振扩散张量成像在神经导航中的初步应用  

Preliminary Application of Diffusion Tensor Magnetic Resonance Imaging in the Neurosurgical Navigation

作　　者：孙敬 刘涛[2] 徐菡[3] 郭静[3] 王冠忠[3] 贡志刚[2] 沈钧康[3] 

机构地区：[1]江苏省苏州市相城人民放射科,江苏苏州215131 [2]苏州大学附属第二医院影像科,江苏苏州215004 [3]苏州大学附属第二医院神经外科,江苏苏州215004

出　　处：《中国CT和MRI杂志》2011年第5期41-44,共4页Chinese Journal of CT and MRI

基　　金：江苏省社会发展计划基金资助(编号:BS2005023)

摘　　要：目的探讨基于磁共振扩散张量成像的纤维束神经导航在脑内病灶切除术中应用价值。方法 21例行纤维束神经导航手术治疗病例,分为解剖导航组(11例)和纤维束神经导航组(10例),年龄48.8±12.2岁;病灶主要位于两侧大脑半球额、顶、枕叶,多数患者存在一定程度肌力障碍。比较两组病例病灶切除率、术后相关功能恢复情况。结果病灶切除率、患者术后功能恢复之间差异有统计学意义(P=0.048、P=0.049)。结论基于磁共振扩散张量成像的纤维束成像有助于对颅内病灶术前手术计划制订;神经纤维束导航有助于提高病灶全切率,保护具有重要功能的白质纤维束。Objective To evaluate the application of diffusion tensor image in neurosurgery,To encourage the application of fiber tracking in neuronavigation and improve the curative effect.Methods 22 patients（male 14cases,female 8 cases,Mean age 48.5 years） who had been underwent neurosurgery for the intracranial lesions had been divided into test group（fiber neuronavigation group） and control group（conventional neuronavigation group）.To compare the curative effects of the two groups.Results The test group is superior to control group in the total resection rate,functional recovery of patients and Karnofsky score.Conclusion DTI makes contribution to the diagnosis and differential of intracranial losions,and provide important imformation for the surgical plan;fiber tract navigation helps increasing the surgical-removed rate and protecting the fiber bundles which have important functions.

关 键 词：磁共振 扩散张量成像 白质纤维束示踪 神经导航 

分 类 号：R445.2[医药卫生—影像医学与核医学] R5[医药卫生—诊断学]