斑点追踪显像、实时三维超声心动图与门控心肌灌注SPECT显像评价左心室收缩同步性的相关性研究  

Study on the correlection between echocardiographic novels and gated myocardial perfusion single-photonemission computed tomography in evaluating left ventricular systolic synchrony

作　　者：方晓燕[1] 孙敏敏[1] 石洪成[2] 舒先红[1] 

机构地区：[1]复旦大学附属中山医院超声心动图室,上海200032 [2]复旦大学附属中山医院核医学科, 上海200032

出　　处：《中华超声影像学杂志》2011年第10期833-837,共5页Chinese Journal of Ultrasonography

基　　金：国家自然科学基金（30972812）;上海市科委“优秀学科带头人”基金（09XD1401000）

摘　　要：目的 探讨斑点追踪显像（speckle tracking imaging,STI）、实时三维超声心动图（real-time three-dimensional echocardiography,RT-3DE）与门控心肌灌注SPECT显像（gated myocardial perfusion single-photon emission computed tomography,GMPS）评价冠心病患者左室收缩同步性的相关性.方法 13例冠心病患者进行STI及RT-3DE检查,获得左室12节段径向应变及圆周应变达峰时间标准差（Trs12-SD,Tcs12-SD）,左室16节段纵向应变达峰时间标准差（Tls16-SD）,左室16节段和12节段达最小容积时间标准差（Tmsv16-SD,Tmsv12-SD）.测量结果与GMPS评价左室收缩同步性参数进行比较.结果 STI参数Trs12-SD与GMPS参数相位标准差、相位宽度正相关（分别为r=0.800,P＜0.05;r=0.607,P＜0.05）；RT-3DE参数Tmsv16-SD与GMPS参数相位标准差、相位宽度相关性更好（分别为r=0.847,P=0.001;r=0.890,P＜0.001）.结论 RT-3DE参数较STI参数与GMPS参数的相关性更好,提示RT-3DE参数有望成为评价左心室收缩同步性的理想指标.Objective To evaluate left ventricular systolic synchrony in patients with coronary artery disease （CAD） by speckle tracking imaging （STI） and real-time three-dimensional echocardiography （RT3DE） and investigate the correlation with ECG-gated myocardial perfusion single-photon emission computed tomography （GMPS）.Methods A total of thirteen patients with CAD diagnosed by coronary angiography underwent STI and RT-3DE examinations.The data was analysed off-line using Qlab 8.0 software.STI systolic synchrony indexes included the standard deviation of times to peak strain in radial and circumferial direction in 12 left ventricular segments （Trs12-SD and Tcs12-SD）,the standard deviation of times to peak longitudinal strain in 16 left ventricular segments （Tls16-SD）.RT-3DE systolic synchrony indexes included the standard deviation of times to the minimum systolic volume in 16 and 12 left ventricular segments （Tmsv16-SD and Tmsv12-SD）.GMPS was performed within one week before or after echocardiography.Phase analysis was performed offline using Emory Cardiac Toolbox software.Peak phase,phase SD,bandwidth,skewness and kurtosis were calculated.Results Trs12-SD derived from STI had a positive correlation with phase SD and bandwidth （ r =0.800,P 〈0.05 ; r =0.607,P 〈0.05）.Tmsv16-SD derived from RT-3DE had a better positive correlation with phase SD and bandwidth （ r =0.847,P =0.001 ; r =0.890,P 〈0.001）.Conclusions Tmsv16-SD derived from RT-3DE had a better correlation with GMPS parameters than STI parameters.RT-3DE assessment of left ventricular systolic parameters is expected to become the ideal synchronization indicator.

关 键 词：超声心动描记术 实时三维 冠状动脉疾病 心室功能 左 斑点追踪显像 体层摄影术 发射型计算机 单光子 

分 类 号：R541.4[医药卫生—心血管疾病]