胆木叶的水溶性成分研究  

Water-Soluble Chemical Constituents from the Leaf of Nauclea officinalis

作　　者：邓世明[1,2] 汤丽昌[2] 王宁[2] 杨先会[1] 

机构地区：[1]海南大学海南省热带生物资源可持续利用国家重点实验室(培育基地),海南海口570228 [2]海南大学海洋学院,海南海口570228

出　　处：《时珍国医国药》2011年第5期1110-1111,共2页Lishizhen Medicine and Materia Medica Research

基　　金：国家科技支撑计划(No.2007BAI27B04)

摘　　要：目的研究中药胆木叶的水溶性成分。方法应用多种色谱方法进行分离纯化,通过1H-NMR、13C-NMR等波谱技术确定化合物的结构。结果从胆木叶乙醇提取物的水溶性成分中分离得到5个化合物,其中4个配糖体。经过波谱和理化性质分析分别鉴定为3,4-二羟基苯甲酸(I)、胡萝卜苷(II)、山萘酚-3-O-(6″-O-α-L-鼠李吡喃糖基)-β-D-葡萄吡喃糖苷(Ⅲ)、芦丁(Ⅳ)和Pumiloside(V)。结论化合物I、Ⅲ和Ⅳ首次从该植物中分离得到。Objective To investigate the water-soluble fraction of the ethanol extract from the leaf of Nauclea officinalis.Methods The chemical constituents were isolated by various chromatography techniques,and structurally elucidated by spectral evidence together with physiochemical analysis.Results Four compounds were isolated from the Water-Soluble fraction of the ethanol extract from the leaf of N.officinalis,and their structures were identified as 3,4-dihydroxybenzoic aci（Ⅰ）,daucosterol（Ⅱ）,kaempferol-3-o-β-D-（6″-O-α-L-rhamnepy ranosyl） glucopyranoside（Ⅲ）,rutin（Ⅳ） and Pumiloside（V）.Conclusion Compounds Ⅰ,Ⅲ and Ⅳ were isolated from N.officinalis for the first time.

关 键 词：胆木 水溶性成分 配糖体 

分 类 号：R284.1[医药卫生—中药学]