天麻素对小鼠的镇静催眠作用  

Effects of Gastrodin on Sedation and Hypnosis of Mice

作　　者：邹宁[1] 吕剑涛 薛仁余[1] 柏新富[1] 徐桂萍 

机构地区：[1]鲁东大学生命科学学院,山东烟台264025 [2]山东省烟台市中医医院,山东烟台264001

出　　处：《时珍国医国药》2011年第4期807-809,共3页Lishizhen Medicine and Materia Medica Research

基　　金：山东省自然科学基金(No.y2006c107)

摘　　要：目的观察天麻素对小鼠自主活动的影响以及天麻素与巴比妥钠对小鼠催眠的协同作用。方法采用镇静、催眠实验方法研究天麻素的镇静、催眠作用。结果天麻素能明显减少小鼠自主活动次数,增加阈下剂量巴比妥钠致小鼠睡眠只数。结论天麻素对小鼠具有明显的镇静、催眠作用。Objective To observe the sedative and hypnotic effect of gastrodin in mice.Methods Effects of gastrodin on the autonomous activity of mice and synergy of gastrodin and sodium pentobarbital were tested.Results Gastrodin obviously decreased the times of autonomous activity of mice,and increased the subthreshold dose of sodium pentobarbital to mouse sleep.Conclusion Gastrodin has obvious effects on the sedation and hypnosis of mice.

关 键 词：天麻素 镇静 催眠 

分 类 号：R284.2[医药卫生—中药学]