中药绿原酸的研究进展  

Advancement of Chlorogenic Acid in Traditional Chinese Medicine

作　　者：王丽萍[1] 郭栋[1] 王果[1] 周宏灏[1] 

机构地区：[1]中南大学临床药理研究所,湖南长沙410078

出　　处：《时珍国医国药》2011年第4期961-963,共3页Lishizhen Medicine and Materia Medica Research

基　　金：国家自然科学基金(No.30801421);重大新药创制专项项目(No.2009ZX09501-032);湖南省科技计划项目(No.2009JT3020);教育部博士点(新教师)基金项目(No.20090162120024)

摘　　要：绿原酸存在于多种植物中。文章从它的吸收、分布、代谢、排泄等药物代谢动力学和抗炎、抗肿瘤、抗菌、抗心血管疾病、抗氧化降血糖等药物效应学等方面对其进行阐述,并对绿原酸的发展前景进行展望。Chlorogenic acids exist in many plants.This paper discussed its pharmacokinetics including absorption,distribution,metabolism,excretion and pharmacodynamics including antiinflammation,anticancer,antibiosis,anticardiovascular-diseases,hypoglycemic activity,antioxidation.In addition,the development of the chlorogenic acids in the future was also forecasted.

关 键 词：绿原酸 药物代谢动力学 药物效应学 

分 类 号：R2-03[医药卫生—中医学]