彩色多普勒超声应用于11～14周胎儿筛查的价值  

The screening value in the first-trimester fetuses by color Doppler flow image

作　　者：王莉[1] 吴青青[1] 陈焰[1] 姚苓[1] 马玉庆[1] 杨文娟[1] 李晓菲[1] 

机构地区：[1]首都医科大学附属北京妇产医院超声科,100026

出　　处：《中华医学超声杂志（电子版）》2011年第1期14-17,共4页Chinese Journal of Medical Ultrasound(Electronic Edition)

基　　金：国家科技支撑计划(2006BAI05A00);首都医学发展科研基金联合资助(2009-3131)

摘　　要：目的探讨彩色多普勒超声用于11～14周胎儿筛查的价值。方法应用彩色多普勒超声对2380例孕11～14周(胎儿头臀长在45～84mm之间)的孕妇进行检查。结果胎儿总数2426例,其中单胎2334例,双胎46例。共发现可疑异常胎儿28例:(1)颈项透明层(NT)≥3.0mm8例。(2)NT≥3.0mm合并其他异常11例。(3)胎儿单纯解剖结构异常8例(1例多发畸形,1例脐膨出,1例胎盘部分性葡萄胎,1例脉络丛囊肿,4例中枢神经系统畸形包括露脑畸形3例、无脑儿1例)。(4)静脉导管血流频谱异常1例。结论彩色多普勒超声检查用于11～14周胎儿筛查能够提供重要的遗传学信息,发现严重的胎儿解剖结构异常。Objective To examine the value of color Doppler flow image（ CDFI） in the screening of first-trimester fetus. Methods Two thousand and three hundred and eighty cases in first-trimester were screened by the color Doppler ultrasonography. Results A total of 2426 fetuses included 46 twins. Twenty- eight fetuses were abnormal including 8 cases of NT~〉3.0 mm and llcases of NT~〉3.0 mm with the other abnormalities. Eight cases of abnormal anatomical structures included 1 case of multiplicitas, 1 case of ceph- alocele, 1 case of partial hydatidiform mole, 1 case of choroid plexus cysts ,4 ease of central nerve system ab- normalities（ 3 cases of exencephaly , 1 case of anencephaly）and 1 case of reversal ＂A＂ wave in ductus veno- sus flow. Conclusion The Color Doppler ultrasonographic examination can provide the important hereditary information for prenatal screening of first-trimester fetus and screen fetal serious abnormal anatomical struc- tures.

关 键 词：产前超声检查 遗传筛查 

分 类 号：R445.1[医药卫生—影像医学与核医学]