改进的解剖M型超声检测Ⅱ型糖尿病患者心肌径向应变率的研究  

Measurement assessment of myocardial radial strain rate in patients with type 2 diabetes mellitus by improved anatomic M-mode echocardiography

作　　者：郭亮[1] 李越[1] 孟素云[1] 陈晓英[1] 

机构地区：[1]中国人民解放军总医院超声科,北京100853

出　　处：《中华医学超声杂志（电子版）》2011年第2期34-38,共5页Chinese Journal of Medical Ultrasound(Electronic Edition)

摘　　要：目的验证改进的解剖M型超声(IAMM)测量左心室短轴心肌径向应变率的可行性。方法选取正常人26例(正常组),Ⅱ型糖尿病患者27例(糖尿病组),分别利用IAMM与斑点追踪成像技术(STI)测量上述研究对象左心室短轴乳头肌平面6个节段的径向应变率,并且评价糖尿病患者的左心室短轴心功能。结果 IAMM与STI测量左心室短轴径向应变率时的相关性和一致性较好,左心室短轴乳头肌平面多数节段的舒张期径向应变率糖尿病组(1.61±0.73、1.62±0.75、1.68±0.80、1.69±0.83、1.81±0.75)均低于正常组(2.07±0.83、2.05±0.60、2.20±0.61、2.36±0.77、2.55±1.14),差异有统计学意义(P<0.05)。结论改进的解剖M型超声心动图可以用于评价左心室短轴径向应变率,糖尿病左心室短轴心功能的早期改变以舒张功能减退为主。Objective To evaluate the feasibility of measuring minor-axis radial strain rate of left ventricular （LV） by improved anatomic M-mode echocardiography （IAMM）. Methods Twenty-six healthy volunteers （HV group） and twenty-seven patients （DM group） with type 2 diabetes mellitus were enrolled in this study. The radial strain rates of 6 segments at LV minor-axis papillary muscle level were measured by IAMM and speckle tracking imaging （STI） technology,respectively,in the two groups,and the rates were also used to assess the LV minor-axis function in the DM group. Results There have been good correlations between the two methods,and the minor-axis radial strain rate of group DM was lower in most of segments during diastole than those of group HV （1.61±0.73 vs 2.07±0.83;162±0.75 vs 2.05±0.60;1.68±0.80 vs 2.20±0.61;1.69±0.83 vs 2.36±0.77;1.81±0.75 vs 2.55±1.14,P0.05）. Conclusion The improved anatomic M-mode echocardiography is competent to evaluate radial strain rate of LV minor-axis,of which the function in patients with diabetes mellitus is determined primarily by reduced diastolic function in the early stage.

关 键 词：超声心动图描记术 2型糖尿病 左心室舒张功能 

分 类 号：R587.1[医药卫生—内分泌] R445.1[医药卫生—内科学]