头孢哌酮/舒巴坦治疗呼吸系统感染175例临床观察  

Cefoperazone/sulbactam in the treatment of respiratoryinfections 175 cases of clinical observation

作　　者：曾华[1] 刘芳 梅雨珍[1] 

机构地区：[1]黄冈职业技术学院医药卫生学院,湖北黄冈438000 [2]湖北省黄石市二医院,湖北黄石435000

出　　处：《黄冈职业技术学院学报》2011年第5期78-79,87,共3页Journal of Huanggang Polytechnic

摘　　要：目的观察头孢哌酮/舒巴坦治疗呼吸系统感染的疗效及安全性。方法对2006年1月～2010年12月175例用头孢哌酮/舒巴坦治疗呼吸系统感染的情况进行回顾性研究,总结其疗效及毒副作用。结果头孢哌酮-舒巴坦的用量每日2g～4g,疗程5～18天;用药后3～6.5天体温下降,体温下降率92.0%;白细胞数升高者用药后85.4%降至正常范围,炎性X线征象52.6%消失或明显吸收好转,痰细菌培养阳性者细菌清除率为85.1%;总有效率为86.9%,无效者中有12例为严重粒细胞缺乏;有16例丙氨酸转氨酶短暂升高,余未见其它副作用。结论头孢哌酮/舒巴坦治疗呼吸系统感染安全有疗效。Cefoperazone/sulbactam in the treatment of respiratory infections efficacy and safety.Methods： January 2006-December 2010 175 cases of cefoperazone/sulbactam in the treatment of respiratory infections were studied retrospectively to summarize the efficacy and toxicity.The results of cefoperazone/sulbactam dosage daily 2g ~ 4g,course of 5 to 18 days;3 to 6.5 days after treatment decreased body temperature,body temperature decreased rate of 92.0%;white blood cell count increased by 85.4% after treatment to normal range,52.6% of X-ray findings of inflammatory disappeared or significantly improved absorption,sputum bacterial culture positive bacterial clearance rate was 85.1%;total effective rate was 86.9%,ineffective in 12 cases of severe neutropenia;16 patients alanyl transient increase in acid transaminase,I was no other side effects.Conclusion： cefoperazone/sulbactam in the treatment of respiratory infections safety effect.

关 键 词：孢哌酮-舒巴坦 呼吸系统感染 疗效 安全性 

分 类 号：R974[医药卫生—药品]