337株呼吸道鲍氏不动杆菌体外药敏结果分析  

In vitro drug susceptibility of 337 strains of Acinetobacter baumannii isolated from sputum samples

作　　者：张齐武[1] 黄晓文[1] 牛淼[1] 刘登科[1] 王延伟[1] 

机构地区：[1]解放军第210医院呼吸内科,辽宁大连116021

出　　处：《中华医院感染学杂志》2011年第22期4826-4828,共3页Chinese Journal of Nosocomiology

摘　　要：目的分析鲍氏不动杆菌的药敏结果,指导临床合理使用抗菌药物。方法收集并分析2008年6月-2010年12月从临床标本中分离的337株鲍氏不动杆菌药敏资料。结果鲍氏不动杆菌对米诺环素敏感率最高,达86.4%;美罗培南敏感率23.1%,占第2位;亚胺培南敏感率22.3%,排第3位;四环素中介率最高,为14.2%;米诺环素耐药率最低,为6.5%;其他抗菌药耐药率波动在71.2%～84.9%。结论鲍氏不动杆菌耐药问题非常严重,应加强监测,根据药敏结果合理使用抗菌药物。OBJECTIVE To investigate the drug sensitivity of 337 Acinetobacter baumannii strains isolated from sputum samples to common antibiotics,and then to provide evidence for reasonable use of antibiotics in clinical practice. METHODS The microbial sensitivity tests of the 337 strains of Acinetobacter baumannii isolated from our hospital from Jun 2008 to Dec 2010 were reviewed and analyzed. RESULTS Minocycline,meropenem and imipenem were the top three active agents against A.baumannii among those antibiotics tested.The sensitivities of A.baumannii to minocycline,meropenem and imipenem were 86.4%,23.1%,22.3%,respectively.Tetracycline had the highest intermediate sensitive rate（14.2%） and minocycline the lowest resistance rate（6.5%） among those antibiotics tested.Resistance rates of the other antibiotics fluctuated between 71.2%～84.9%. CONCLUSION A.baumannii is resistant to most antibiotics tested,it should strengthen the monitoring and use antibiotics rationally in accordance with the drug susceptibility.

关 键 词：鲍氏不动杆菌 药物敏感试验 抗菌药物 耐药性 

分 类 号：R378[医药卫生—病原生物学]