肺动脉高压分类、发病机制及治疗  

Classification and pathogensis and treatment of pulmonary arterial hypertension

作　　者：肖谊[1] 邢西迁[1] 张红艳[1] 吴绪伟[1] 

机构地区：[1]昆明医学院附属延安医院呼吸一科,650051

出　　处：《国际呼吸杂志》2011年第20期1590-1593,共4页International Journal of Respiration

基　　金：云南省教育厅科学研究基金项目（2010C091）;国家自然科学基金项目（81100037）

摘　　要：肺动脉高压（pulmonary arterial hypertension，PAH）是由多种病冈引起并有复杂发病机制的疾病。表现为肺循环的压力和阻力的增加，最终导致右心衰竭，治疗棘手。近年来，PAH的诊断、分类不断更新、完善；发病机制、病理生理、分子生物学的研究不断深入；临床治疗药物也在不断探索。为PAH的诊治开拓了广阔的前景。本文复习文献，对目前PAH研究现状及进展进行阐述。Pulmonary arterial hypertension （PAH） is a disease by variety of causes, and its pathogensis is complex. In which pulmonary arterial obstruction increases pulmonary vascular resistance, which leads to right ventricular failure, the therapy troublesome. In recent years, The diagnosis and classification of PAH was updated, with deeply researching on the pathogcnsis, pathophysiology and molecular biology, The treatment is researching constantly. To provide a wide prospect for PAH and diagnosis. This article reviews literature, to explain the recent advances on PAH.

关 键 词：肺动脉高压 诊断 分类 发病机制 治疗 

分 类 号：R544.16[医药卫生—心血管疾病]