发热性溃疡性Mucha-Habermann病1例  

A Case of Febrile Ulcerone-Crotic Mucha-Habermann Disease

作　　者：张斌[1,2] 杨海珍[1] 伦文辉[2] 涂平[1] 

机构地区：[1]北京大学第一医院皮肤性病科,北京100034 [2]首都医科大学附属北京地坛医院,北京100015

出　　处：《中国皮肤性病学杂志》2011年第11期892-893,895,共3页The Chinese Journal of Dermatovenereology

摘　　要：患儿男,9岁,四肢反复皮疹伴疼痛,间断发热2年余,加重1年。患儿四肢可触及暗红色结节、斑块,部分皮损伴溃疡及萎缩性瘢痕,无关节痛、淋巴结及肝脾肿大。组织病理:真皮全层小血管增多,血管周围淋巴细胞浸润伴界面皮炎,亦可见水肿及灶性表皮坏死,未见淋巴细胞非典型性。诊断为发热性溃疡性Mucha-Habermann病。患儿男,9岁,四肢反复皮疹伴疼痛,间断发热2年余,加重1年。患儿四肢可触及暗红色结节、斑块,部分皮损伴溃疡及萎缩性瘢痕,无关节痛、淋巴结及肝脾肿大。组织病理:真皮全层小血管增多,血管周围淋巴细胞浸润伴界面皮炎,亦可见水肿及灶性表皮坏死,未见淋巴细胞非典型性。诊断为发热性溃疡性Mucha-Habermann病。A 9-year-old boy with recurrent eruptions on his extremities with pain, discontinuity fever for about 2 years, and aggravated about 1 year. We could see several black red nodus and plaques on his legs and arms, some ulcers and atrophic scar among them. He denied joint paining. There were no lymphadenectasis and hepatosplenomegaly. Histopathological examination revealed increased small vessels in dermis, perivascular regional lymphocyte infiltrations with interface dermatitis, focal epidermal edema and necrosis, there was no atypical lymphocytes. Febrile ulcerone-croticMucha-Habermann disease was diagnosed.

关 键 词：发热性溃疡性Mucha—Habermann病 急性痘疮样苔藓样糠疹 表皮坏死 发热 

分 类 号：R758.69[医药卫生—皮肤病学与性病学]