蛋白尿与肾脏损伤  

Renal toxicity of proteinuria

作　　者：戴厚永[1,2] 刘必成[1] 

机构地区：[1]东南大学附属中大医院肾内科东南大学肾脏病研究所,南京210009 [2]南通大学附属医院肾内科

出　　处：《肾脏病与透析肾移植杂志》2011年第5期467-469,共3页Chinese Journal of Nephrology,Dialysis & Transplantation

基　　金：国家自然科学基金重点项目(81130010)

摘　　要：蛋白尿是大多数慢性肾脏病(CKD)共同的临床表现,其在CKD进展和肾小管间质纤维化过程中发挥了重要的作用。更好地理解蛋白尿的肾毒性作用机制,对于CKD防治将具有十分重要的意义。ABSTRACT Proteinuria is one of the most common manifestations for patients with chronic kidney disease（CKD）. Recent studies have suggested that proteinuria might serve as a nephrotoxic factor in mediating tubulointerstitial inflammation, while its potential mechanism is still of much interesting topic for the study. In this review, we summarized the updated insights on proteinuria induced tubularinterstitial damage.

关 键 词：蛋白尿 肾小管间质纤维化 炎症 

分 类 号：R692[医药卫生—泌尿科学]