椎体成形术中椎体骨密度对骨水泥弥散体积的影响  

Effect of vertebral bone mineral density on bone cement distribution volume in percutaneous vertebroplasty

作　　者：张亮[1] 高梁斌[2] 李健[1] 王簕[1] 张志[1] 尹飚[1] 杨波[1] 

机构地区：[1]广州医学院第三附属医院骨科,510150 [2]中山大学附属第二医院骨外科,广州市510120

出　　处：《中国脊柱脊髓杂志》2011年第11期915-918,共4页Chinese Journal of Spine and Spinal Cord

基　　金：广东省医学科研基金项目(编号:A2011276);广州市医药卫生科技项目(编号:2009-YB-165)

摘　　要：目的:探讨椎体成形术中椎体骨密度对骨水泥弥散体积的影响。方法:18例胸腰椎压缩骨折患者,术前均行骨折椎体双能X线骨密度仪测定,根据WHO骨质疏松症诊断标准分为骨密度正常组(A组)、骨密度减低组(B组)及骨质疏松组(C组),每组6例,采用经伤椎单侧椎弓根行椎体成形术,术中注入相同状态和批次骨水泥2.5ml,术后采用64排CT扫描椎体,计算骨水泥注射体积及弥散体积。结果:所有患者均顺利完成手术并均成功注2.5ml骨水泥,CT计算骨水泥注射体积:A组2.460±0.116cm3,B组2.450±0.038cm3,C组2.457±0.037cm3;骨水泥在椎体中弥散体积:A组为6.717±1.127cm3,B组为5.650±0.669cm3,C组为4.617±0.542cm3。三组骨水泥弥散体积均大于同组注射体积(P<0.01);三组间骨水泥注射提及比较均无统计学差异(P>0.05)。弥散体积比较均有统计学差异(P<0.05),A组弥散体积最大。结论:椎体成形术中骨水泥弥散体积大于骨水泥注射体积;椎体骨密度与椎体内骨水泥弥散体积密切相关,骨密度越高,弥散体积越大。Objective：To investigate the effect of vertebral bone mineral density on bone cement distribution volume in percutaneous vertebroplasty.Method：The vertebral bone mineral density（BMD） of patients with tho- racolumbar vertebral compression fracture was measured preoperatively by dual energy X-ray absorptiometry. According to the diagnostic criteria of osteoporosis of the WHO,18 patients were selected and divided into three groups：normal BMD group（group A）,low BMD group （group B） and osteoporosis group（group C）,with each group of 6 cases.All patients underwent unilateral vertebral vertebroplasty,with 2.5ml bone cement injec- tion for each patient.All patients experienced CT scan postoperatively,and the volume of bone cement diffusion was caleulated.Result：2.5ml bone cement was injected into each of the patients successfully.The mean injection volume of bone cement in group A was 2.460±0.116cm^3,2.450±0.038cm^3 in group B,and 2.457± 0.037cm^3 in group C.The mean diffusion volume of bone cement in group A was 6.717±1.127cm^3,5.650± 0.669cm^3 in group B,and 4.617±0.542cm^3 in group C,with bigger diffusion volume than the injection volume （P〈0.01）.Meanwhile,the biggest diffusion volume was noted in group A,and the smallest diffusion volume in group C, which showed significant difference（P〈0.05）.Conelusion：The bone cement diffusion volume is bigger than injection volume in vertebroplasty.The BMD of vertebral body is closely associated with the diffusion volume of bone cement.The higher BMD of the vertebral body,the bigger diffusion volume of bone cement.

关 键 词：椎体成形术 骨密度 骨水泥 弥散体积 注射体积 

分 类 号：R683.2[医药卫生—骨科学]