电针对腰神经根受压兔肌肉状态及坐骨神经运动传导速度的影响  

Correlation study on effects of electroacupuncture on the muscle condition and MNCV in rabbits with lumbar nerve root compression

作　　者：吴耀持[1] 孙懿君[1] 张峻峰[1] 黄承飞[1] 谢艳艳[1] 周景辉[1] 李石胜[1] 

机构地区：[1]上海交通大学附属第六人民医院针推伤科,上海200233

出　　处：《中国针灸》2011年第11期1009-1014,共6页Chinese Acupuncture & Moxibustion

基　　金：上海市科学技术委员会"中医药现代化专项"资助项目:09dZ1971800

摘　　要：目的:观察电针对腰神经根受压的肌肉状态以及肌肉电生理的影响,探讨其作用机制。方法:将24只新西兰白兔随机分为正常组、模型组、药物组和电针组。模型组、药物组和电针组通过手术建立兔腰神经根受压模型;正常组不予造模及治疗。药物组口服洛索洛芬钠片,30 mg/d;电针组予以电针疗法,针刺L5、L6"夹脊"穴,均连续治疗14 d。测定造模前、造模后及治疗后双侧肌肉状态,并检测肌电图及神经传导速度。结果:造模后,电针组、药物组及模型组的肌电图出现自发电位,插入电位增多;右侧肌肉力量-位移激活和放松状态数值明显降低。治疗后,电针组、药物组及模型组运动神经传导速度及诱发电位波幅明显减低,但相较其他组,电针组更接近正常组;电针组、药物组右侧肌肉力量-位移激活和放松状态数值升高接近正常组,其中电针组放松状态数值更接近正常组。结论:电针能改善模兔受损神经根所支配肌肉的力量-位移状态,改善肌肉电生理状态,恢复受压神经根运动神经传导速度及诱发电位波幅。Objective To observe the effects of electroacupuncture on the muscle condition and electrophysiology of the muscle in rabbits with lumbar nerve root compression and to explore potential mechanisms. Methods Twenty-four New Zealand white rabbits were randomly divided into a normal group, a model group, a medication group and an electroacupuncture group. The rabbit model with lumbar nerve root compression was established in the model group, the medication group and the electroacupuncture group. The model and the treatment were not produced in the normal group. The medication group was treated with oral administration of Loxoprofen tablets at a dose of 30 mg each day for 14 days. The electroacupuncture group was treated with electroacupUncture at ＂Jiaji＂ （EX-B 2） of L5 and L6 for 14 days. The hibateral muscle condition before and after making model and after treatment was detected and the electromyogram and the nerve conduction velocity （NCV） were observed. ResuLts The spontaneous potential and the insertion potential were increased in the model group, the medication group and the electroacupuncture group after making model. The value of the activation and the relaxed condition of the strengthcreep （ARCSC） in the right muscle was significantly decreased. The motor nerve conduction velocity （MNCV） and the wave amplitude of evoked potential （WAEP） were significantly decreased in the model group, the medica- tion group and the electroacupuncture group after treatment, but the value of MNCV and WAEP in the electroacupuncture group, and ARCS（] in the right muscle in the electroacupuncture group and the medicine group were closed to those level in the normal group, among them, the relaxed condition in the electroacupuncture group was more close to the level in the normal group. Conclusion Eleetroacupuncture can improve the strength-creep condition of the muscle that damage nerve place controls and the electrophysiology and the wave amplitude of evoked potential in the compression nerve root.

关 键 词：腰脊神经根受压 模型 兔 电针 肌电图 肌张力 

分 类 号：R246.2[医药卫生—针灸推拿学]