中药复方三黄胶囊治疗HIV/AIDS患者的临床观察  

Clinical observations on HIV/AIDS treated with Chinese herb combination Sanhuang capsule

作　　者：赵鹏[1] 张昕[1] 赵华[1] 张新伟[1] 张志梅[1] 

机构地区：[1]解放军第302医院,北京100039

出　　处：《现代中西医结合杂志》2011年第33期4193-4194,4197,共3页Modern Journal of Integrated Traditional Chinese and Western Medicine

摘　　要：目的评价中药复方三黄胶囊治疗艾滋病携带者/艾滋病(HIV/AIDS)患者的疗效和安全性。方法采用随机、双盲的临床观察方法,试验组32例,对照组16例,分别予标准剂量与低剂量复方三黄胶囊做平行对照,共服用36周。结果 36周时试验组CD4+T细胞升高比对照组明显,2组比较有显著性差异;试验组HIV病毒载量下降较明显,2组比较有显著性差异;试验组临床症状改善情况较对照组明显,2组比较有显著性差异;2组均未发现明显毒副反应。结论复方三黄胶囊能抑制HIV复制,提高HIV/AIDS患者的CD4+T细胞数,显著改善HIV/AIDS患者的临床症状,提高生存质量;并且不良反应少,依从性良好,不易造成抗药。Objective It is to assess the effectiveness and safety of Chinese herb Combination Sanhuang capsule for treatment of HIV/AIDS. Methods Prospective,randomized,low dosage-controlled and double blinded observations were conducted.Test group with 32 cases received Combination Sanhuang capsule while control group with 16 cases received low dosage of Combination Sanhuang capsule;the treatment last for 36 weeks in either groups. Results After 36 weeks,the mean value of CD4 increased more significantly in test group than in control group（P〈0.05）;the viral loads were declined in test group than in control group（P〈0.05）;test group had better effect in improving symptoms and signs than control group（P0.05）.No obvious toxic side effect was found in both groups. Conclusion Combination Sanhuang capsule has significant effect in improving clinical symptoms and immunological function,stabilizing viral loads.

关 键 词：艾滋病病毒感染者/艾滋病患者 中药治疗 复方三黄胶囊 

分 类 号：R512.91[医药卫生—内科学]