中西医结合治疗100例哮喘患者的临床疗效与生活质量评价  

Clinical effect assessment of integrated TCM and western medical treatment for 100 patients with bronchial asthma

作　　者：郝一鸣[1] 王忆勤[1] 洪毓键[1] 闫秀丽[1] 张晓丹[1] 翁诗婷[1] 于明杰[1] 金美玲[2] 顾洪亮[3] 

机构地区：[1]上海中医药大学中医四诊信息化实验室,上海201203 [2]复旦大学附属中山医院,上海200032 [3]上海交通大学附属第九人民医院,上海200011

出　　处：《中华中医药杂志》2011年第11期2748-2751,共4页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：上海市第三期重点学科(No.S30302)~~

摘　　要：目的:对中西医结合治疗支气管哮喘(简称哮喘)患者临床疗效与生活质量进行评价,并以单纯西医治疗为对照,探讨哮喘中西医结合治疗的优势。方法:采集哮喘患者包括成人治疗组50例和儿童治疗组50例,均以中西医结合治疗;另采集成人对照组45名和儿童对照组40名,均以单纯西医治疗。通过观察与记录4组患者治疗后综合疗效、肺功能及生命质量状况的变化,评价中西医结合治疗哮喘的临床疗效与生活质量。结果:①成人治疗组治疗后综合疗效评价与对照组无显著性差异,肺功能指标PEF%显著优于对照组。儿童治疗组治疗后综合疗效评价和肺功能的改善程度与对照组无显著性差异。②成人治疗组治疗后6个月、1年、2年3个时间段的生活质量与对照组无显著性差异。儿童治疗组治疗后3个月、6个月、1年、2年4个时间段的生活质量显著优于对照组。结论:中西医结合治疗哮喘可显著改善患者临床疗效及肺功能,同时在改善患者生活质量状况上具有一定优势。Objective： To investigate the advantages for curing patients with Bronchial Asthma（BA） by integrated treatment of both Traditional Chinese Medicine（TCM） and western medicine,clinical efficacy and evaluating changes of quality of life were used as comprehensive clinical efficacy and patients receiving purely western medicine were collected as control group.Methods： 50 adults and 50 children suffering from BA and receiving both TCM and western medicine treatment were collected as adult treatment group and children treatment group.For adult control group and children control group,45 adults and 40 children who were receiving purely western medicine treatment were collected.During observation,pulmonary function,evaluating changes of quality of life as well as the clinical efficacy for patients with BA were recorded as comprehensive clinical efficacy for integrated TCM and western medical treatment for patients with BA.Results： ①After integrative medical treatment,for the comprehensive clinical efficacy,there was no significant difference between adult treatment group and the adult control group.For pulmonary function,PEF% of adult treatment group was significantly better than the adult control group.After integrative medical treatment,for the comprehensive clinical efficacy and pulmonary function,there was no significant difference between children treatment group and the children control group.②After 6-month,1-year and 2-year-peroid,for evaluating changes of quality of life,there was no significant difference between adult treatment group and adult control group.After 3-month,6-month,1-year and 2-year-peroid,children treatment group＇s quality of life was significantly better than the children control group.Conclusion： There was significant improvement in both clinical efficacy and pulmonary function for BA patients receiving integrated TCM and western medical treatment,which might also have advantages in improving patients＇ quality of life.

关 键 词：哮喘 中西医结合 疗效 肺功能 生活质量 

分 类 号：R562.25[医药卫生—呼吸系统]