耐碳青霉烯类鲍氏不动杆菌所致老年患者医院获得性肺炎分析  

Analysis of hospital-acquired pneumonia caused by carbapenem-resistant Acinetobacter baumannii in elderly patients

作　　者：夏静静[1] 方向群[1] 

机构地区：[1]解放军总医院南楼呼吸科,北京100853

出　　处：《中华医院感染学杂志》2011年第21期4589-4591,共3页Chinese Journal of Nosocomiology

摘　　要：目的分析耐碳青霉烯类鲍氏不动杆菌(CRAB)所致老年患者医院获得性肺炎的临床特点。方法对2008年1月-2011年3月,CRAB所致老年患者医院获得性肺炎63例进行回顾性分析。结果 CRAB所致老年患者医院获得性肺炎多发生在有基础疾病患者,经头孢哌酮/舒巴坦或含有头孢哌酮/舒巴坦抗菌药物组合治疗的患者,30d存活率为94.44%,显著高于经其他抗菌药物治疗患者的70.37%(P<0.05);死亡患者APACHEⅡ评分为(24.78±4.35)分,显著高于存活患者的(18.32±6.92)分,差异有统计学意义(P<0.05)。结论头孢哌酮/舒巴坦治疗老年患者CRAB医院获得性肺炎有一定疗效,APACHEⅡ评分与老年患者CRAB医院获得性肺炎预后有关。OBJECTIVE To summarize the clinical characteristics of hospital-acquired pneumonia （HAP） caused by Carbapenem-resistant Acinetobacter baumannii （CRAB） in elderly patients. METHODS A retrospective study was conducted in elderly patients suffering from HAP caused by CRAB from Jan 1, 2008 to Mar 30, 2011. RESULTS HAP caused by CRAB in elderly often occurred in patients complicated with other diseases. The 30-day survival rate of patients treated with cefoperazone/sulbactum or eefoperazone/sulbactum-containing antibiotic combinations was 94.44%, which was significantly higher than that of the other group （70.37%） （P〈0.05）; APACHEⅡ score of the patients died was （24. 78 ± 4.35）, which was significantly higher than that （18.32±6.92） of the survival patients （P〈 0. 05）. CONCLUSION Cefoperazone/sulbactum is effective in the treatment for elderly patients suffering from HAP caused by CRAB. APACHE II score is a predictive factor in elderly patients suffering from HAP caused by CRAB.

关 键 词：医院获得性肺炎 鲍氏不动杆菌 耐碳青霉烯类 老年患者 

分 类 号：R378[医药卫生—病原生物学]