新生儿ABO溶血病相关母亲因素分析  

Correlation factor analysis on haemolytic disease of the newborn

作　　者：任晓坤[1] 史天威[2] 余红星[3] 

机构地区：[1]郑州市第三人民医院检验科,郑州450000 [2]郑州人民医院,郑州450000 [3]中山大学公共卫生学院,广州510080

出　　处：《中国优生与遗传杂志》2011年第11期87-88,共2页Chinese Journal of Birth Health & Heredity

摘　　要：目的观察分析孕妇血清IgG抗A(B)效价、妊娠次数及年龄因素与新生儿溶血病的相关性。方法检测母婴血型不合孕妇血清IgG抗A(B)效价,分别统计不同IgG抗A(B)效价的孕产妇中发生因ABO血型不合所致的新生儿溶血病的比率,并比较不同妊娠次数、不同年龄段的孕妇发生新生儿溶血的比率。结果孕妇不同血清IgG抗A(B)效价时、不同妊娠次数时及孕妇的不同年龄段时发生新生儿ABO溶血病的比率之间均有统计学差异(P<0.05),随着孕妇血清IgG抗A(B)效价的增高、妊娠次数的增加及孕妇年龄的增加,新生儿ABO溶血病的发病也增多。结论为保障母婴安全,减少新生儿溶血病的发生率,有条件时检测孕妇血清IgG抗A(B)效价,并尽量减少妊娠次数及避免高龄怀孕。Objective ： Observing the correlation of haemolytic disease of the newborn to the difference IgG anti - A （B） potency, number of pregnancies and conceptional ages in the pregnant women. Methods ： Detecting IgG anti - A （B） potency of pregnant women blood type in compatibility with their newborn. Observing the proportion of haemolytic disease of the newborn in pregnant women with the difference IgG anti - A （B） potency. And observing the proportion in the pregnant women with difference number of pregnancies and conceptional ages. Results ： There is statistic difference between haemolytic disease of the newborn and the difference IgG anti - A （B） potency, number of pregnancies and conceptional ages （P 〈 0. 05 ）. Conclusions ： The IgG anti - A （B） potency should be detected and many times pregnancies and pregnancy in great ages should be avoided to decrease haemolytic disease of the newborn.

关 键 词：新生儿溶血病 IGG抗A(B) 妊娠次数 妊娠年龄 

分 类 号：R722.1[医药卫生—儿科]