血清高敏C反应蛋白、低密度脂蛋白与2型糖尿病血管病变的相关性研究  

Correlation Study of High-sensitivity C-reactive Protein hs-CRP,LDL-C and T2DM Patients with Vascular Disease

作　　者：鲁礴[1] 张萍[1] 杨玉梅[1] LU Bo, ZHANG Ping, YANG Yu-mei （Xiangfan Hospital,Xiangyang City Dongfeng Motor Co.Ltd,Xiangfan 441000, China）

机构地区：[1]湖北襄阳市东风汽车公司襄樊医院,湖北襄樊441000

出　　处：《医学信息》2011年第21期120-121,共2页Journal of Medical Information

摘　　要：目的探讨血清高敏C反应蛋白（high—sensitivityc—reactiveproteinhs—cRP）、低密度脂蛋白（LDL—c）与2型糖尿病（T2DM）血管病变的关系。方法选取2型糖尿病患者102例．其中2型糖尿病并发血管病变组（A组）50例，无血管病变组（B组）52例，另选100例健康者为对照组（c组）。分别测定三组患者血清高敏C反应蛋白、低密度脂蛋白水平。结果2型糖尿病组高敏C反应蛋白、低密度脂蛋白水平与健康对照组比较明显升高（P〈O．05）；并发血管病变患者高敏C反应蛋白、低密度脂蛋白水平高于非血管病变（P〈O．03）。结论血清高敏C反应蛋白、低密度脂蛋白的检测水平对预测2型糖尿病患者发生血管病变有着重要的临床意义。Objective Discussing the relation in serum high-sensitivity c-reactive protein, LDL-C and type 2 diabetic patients with vascular disease. Methods To test the serum hs-CRP and lipid in 52 type 2 diabetic patients with vascular disease（group A）, 50 type 2 diabetic patients with non-vascular disease（group B） and 100 normal controls（group C）. Results The hs-CPR, LDL-C are significantly higher in type 2 diabetic patients. Compared with the healthy control group. The difference is significant （P〈0.05）. In patients with type 2 diabetes, the levels of hs-CRP and LDL-C in group with vascular disease complication are significantly higher in the group with non- vascular disease complication （P〈0.05）. Conclusions Determination of hs-CRP and LDL-C has important clinical value in predicting complications of vascular disease in tvoe 2 diabetic natients.

关 键 词：2型糖尿病 高敏C反应蛋白 低密度脂蛋白 

分 类 号：R587.2[医药卫生—内分泌;医药卫生—临床医学;医药卫生—内科学]