复方祛疤凝胶中三七提取工艺的研究  

Study on Extraction Process of Panax Notoginseng in Compound Quba Gel by Orthogonal Design

作　　者：吴圣琴[1] 李东芬[1] 尹蓉莉[1] 王宝才[1] 陈金玉[1] 陈海亭[1] 

机构地区：[1]成都中医药大学药学院,四川成都611137

出　　处：《成都中医药大学学报》2011年第3期78-80,共3页Journal of Chengdu University of Traditional Chinese Medicine

摘　　要：目的:筛选复方祛疤凝胶中三七的最佳提取工艺。方法:通过前期对提取方法的考察,确定了复方祛疤凝胶中三七应采用回流法进行提取,在本研究中通过正交试验设计,以三七皂苷R1、人参皂苷RgM1、人参皂苷Rb1的含量及干膏率为考察指标,进行多指标综合评分,最终筛选出复方祛疤凝胶中三七的最佳提取工艺。结果:三七的最佳提取工艺为:加10倍量50%乙醇为溶剂回流提取2次,每次1.5 h。结论:验证试验表明,该工艺稳定、可行,可以作为复方祛疤凝胶中三七的提取工艺。Objective：To screen the best extraction method of Panax notoginseng for compound quba gel.Methods：The Panax notoginseng in compound quba gel was extracted by refluxing,after preliminary study on the extraction method.In this study,the contents of notoginsenoside R1,ginsenoside Rg1,ginsenoside Rb1 and dry ointment were considered as the indicators for Multi-index comprehensive evaluation to optimize the extraction condition according to orthogonal design.Results：The optimum extraction process： adding 10 times of 50% ethanol,refluxing for 2 times（1.5h for each time）.Conclusion：The selected optimum Panax notoginseng extraction method is stable and highly efficient,and can be used as extraction process of Panax notoginseng compound quba gel.

关 键 词：三七 正交试验 三七皂苷R1 人参皂苷RB1 人参皂苷RG1 

分 类 号：O6-332[理学—化学] R28[医药卫生—中药学]