创伤性脑损伤患者肠屏障功能研究现状  

Research of intestinal barrier function among patients with traumatic brain injury

作　　者：谢彩霞[1] 朱京慈[2] 尹华华[2] 石荷叶[1] 蔡王婷[1] 李忻宇[1] 

机构地区：[1]四川省医学科学院四川省人民医院神经外科,成都市610072 [2]第三军医大学护理学院,重庆市400038

出　　处：《护理管理杂志》2011年第11期792-794,共3页Journal of Nursing Administration

基　　金：重庆市自然科学基金计划项目(CSTC;2008BB5289)

摘　　要：文章归纳了肠屏障的组成和创伤性脑损伤后肠黏膜结构的病理改变等关键问题。指出了肠黏膜缺血缺氧和缺血再灌注、炎症介质、内毒素、饥饿和营养不良是创伤性脑损伤肠屏障功能障碍的原因,并综述了肠内营养对其保护作用的主要研究进展。This article summarized the key issues of the composition of the intestinal barrier and pathological changes of intestinal mucosa structure aftertraumatic brain injury. It pointed out that the main causes of intestinal harrier dysfunction with traumatic brain injury included intestinal mucosal ischemia and hypoxia,ischemia - reperfusion,inflammatory mediators, endotoxin, hunger or malnutrition. It overvicwcd the protective effect of enteral nutrition on intestinal barrier after traumatic brain injury.

关 键 词：创伤性脑损伤 肠屏障 肠内营养 

分 类 号：R651.15[医药卫生—外科学]