Esophageal mucosal lesion with low-dose aspirin and prasugrel mimics malignancy: A case report  

作　　者：Gui-Fen Ma Hong Gao Shi-Yao Chen 

机构地区：[1]Department of Gastroenterology, Zhongshan Hospital Fudan University, Shanghai200032, China

出　　处：《World Journal of Gastroenterology》2011年第35期4048-4051,共4页世界胃肠病学杂志（英文版）

摘　　要：Dual antiplatelet therapy consisting of low-dose aspirin (LDA) and other antiplatelet medications is recommended in patients with coronary heart disease, but it may increase the risk of esophageal lesion and bleeding. We describe a case of esophageal mucosal lesion that was difficult to distinguish from malignancy in a patient with a history of ingesting LDA and prasugrel after implantation of a drug-eluting stent. Multiple auxiliary examinations were performed to make a definite diagnosis. The patient recovered completely after concomitant acid-suppressive therapy. Based on these findings, we strongly argue for the evaluation of the risk of gastrointestinal mucosal injury and hemorrhage if LDA therapy is required, and we stress the paramount importance of using drug combinations in individual patients.Dual antiplatelet therapy consisting of low-dose aspirin （LDA） and other antiplatelet medications is recommended in patients with coronary heart disease, but it may increase the risk of esophageal lesion and bleeding. We describe a case of esophageal mucosal lesion that was difficult to distinguish from malignancy in a patient with a history of ingesting LDA and prasugrel after implantation of a drug-eluting stent. Multiple auxiliary examinations were performed to make a definite diagnosis. The patient recovered completely after concomitant acid-suppressive therapy. Based on these findings, we strongly argue for the evaluation of the risk of gastrointestinal mucosal injury and hemorrhage if LDA therapy is required, and we stress the paramount importance of using drug combinations in individual patients.

关 键 词：Esophageal injury Low-dose aspirin PRASUGREL Gastrointestinal hemorrhage Drug-eluting stent 

分 类 号：Q64[生物学—生物物理学] TQ460.72[医药卫生—药物分析学]