不同HbA1c水平的2型糖尿病患者动态血糖分析  

The analysis of dynamic glucose characteristics in type 2 diabtetic patients with different concentration of HbA_1c

作　　者：孟健 葛军 俞春芳 徐凌 顾庆 

机构地区：[1]市东医院内分泌代谢科,上海200438

出　　处：《中国糖尿病杂志》2011年第11期816-818,共3页Chinese Journal of Diabetes

摘　　要：目的利用动态血糖监测系统(CGMS)探讨不同HbA_1c水平T2DM患者的血糖特点。方法将178例T2DM患者按HbA_1c水平分为3个组,通过CGMS进行血糖监测。结果各组HbA_1c与全天平均血糖值(24hMBG)均有相关性(P<0.05),与平均血糖漂移幅度(MAGE)无相关性。HbA_1c≤7.5%时,餐后血糖与之相关性较好(P<0.05)。HbA_1c>7.5%时,与三餐前血糖相关性较好(P<0.05)。结论 HbA_1c代表血糖的整体水平,但不能反映血糖的稳定性,而CGMS可反映血糖的波动规律。HbA_1c和CGMS联合应用更加有利于血糖的综合管理。Objective To study the characteristics of blood glucose in type 2 diabetic patients by continuous glucose monitoring system（CGMS）. Method 178 cases of type 2 diabetic patients were divided into three group and blood glucose was measured by CGMS for 3 days. Results （1） 24h mean blood glucose had a correlation with HbA1c（P〈0. 05）, but the mean amplitude of glucose excursion （MAGE） is independent of HbA1c. （2）When the HbA1c≤7.5%, postprandial glucose had a correlation with MAGE（P〈0.05）. The preprandial glucose had better correlation when HbA1 c〉7.5%（P〈0.05）. Conclusions （1）The mean daily glycemia highly correlates with HbA1c. （2）Combined application of HbA1 c and CGMS is beneficial to glucose management.

关 键 词：糖尿病 2型 糖化血红蛋白 动态血糖监测系统 

分 类 号：R587.1[医药卫生—内分泌]