5小时口服葡萄糖耐量试验在诊断餐后低血糖中的应用  

The application of 5 hours oral glucose tolerance test in diagnosising postprandial hypoglycemia

作　　者：黄菊芳[1] 蒋培培[1] 王鹂[1] 彭妙官[1] 许燕莉[1] 黎福梅[1] 廖志红[1] 

机构地区：[1]中山大学附属第一医院东山院区内科,广州510080

出　　处：《中国糖尿病杂志》2011年第11期844-846,共3页Chinese Journal of Diabetes

摘　　要：目的在有或无疑似餐后低血糖症状的受试者中进行5小时口服葡萄糖耐量试验(5hOGTT),探讨OGTT特征及其临床应用价值。方法共纳入27例有疑似餐后低血糖症状的受试者和41例无餐后低血糖症状的受试者,均行82.5g葡萄糖的5hOGTT。结果在无餐后低血糖症状的受试者中共筛查出低血糖6例。在有疑似餐后低血糖的受试者中共筛查出低血糖17例,低血糖再现率83%。诊断服糖后低血糖的人群中IGT伴发率达30%。结论与无餐后低血糖症状人群相比,有疑似餐后低血糖人群中服糖后低血糖的发生率高达63%,服糖后低血糖病例的IGT伴发率达29%。对有疑似餐后低血糖病例进行4hOGTT低血糖筛查敏感性达100%。Objective To discuss the characteristics and clinical value of OGTT, 5-h OGTT was carried out in subjects with or without suspected postprandial hypoglycemia symptoms. Methods 27 subjects with suspected postprandial hypoglycemia symptoms and 41 subjects without postprandial hypoglycemia symptoms accepted 82.5g 5-h OGTT. Results In group without postprandial hypoglycemia symptoms, 6 cases hypoglycemia were detected. In group with suspected postprandial hypoglycemia symptoms, 17 cases hypoglycemia were detected. The reappearance rate of hypoglycemia was 83%. In all hypoglycemia cases, the incidence of IGT reached 30%. Conclusion As compared to the group without postprandial hypoglycemia symptoms, the incidence of hypoglycemia in the group with suspected post-prandial hypoglycemia symptoms is higher, reaching 63%. At the same time, the incidence of IGT reaches 29% . In patients with suspected postprandial hypoglycemia symptoms, the sensitivity of detecting hypoglycemia reaches 100% by 4-h OGTT.

关 键 词：口服葡萄糖耐量试验 餐后低血糖 

分 类 号：R587.1[医药卫生—内分泌]