单采与手工制备的新鲜冰冻血浆的质量比较  

Comparison of the quality of fresh frozen plasma prepared by apheresis and that from whole blood

作　　者：王世春[1] 李兵[1] 赵树铭[1] 

机构地区：[1]第三军医大学西南医院输血科,重庆400038

出　　处：《中国输血杂志》2011年第10期842-843,共2页Chinese Journal of Blood Transfusion

摘　　要：目的探讨单采和手工新鲜冰冻血浆(FFP)的质量差异。方法运用常规检验方法测定单采和手工FFP(各20份)的凝血因子(Fib及FⅧ)、部分生化指标(TP、LDH、K+、Na+及Cl-)、游离血红蛋白(FHb)及pH,并进行对比分析。结果 2种冰冻血浆FHb、K+、Na+、Cl-及Plt含量差异具统计学意义,其他检测指标在两者间差异不具统计学意义,单采FFPFⅧ活性比手工FFP略高。结论单采与手工FFP具有相同的质量,单采FFP的凝血因子活性略优于手工FFP。Objective To compare the quality of fresh frozen plasma prepared by apheresis and that from whole blood.Methods Plasma prepared from apheresis（n=20） and donated whole blood（n=20） were stored in-30℃ refrigerator before testing.Coagulation factors（FⅧ,Fib） ,biochemical parameters（TP,LDH,K＋,Na＋,Cl-,FHb,pH） and Plt counts were determined.Results There were significant differences between the levels of FHb,K＋,Na＋,Cl-,Plt counts,but all could meet the current quality standards.In comparison to plasma prepared by centrifugation of donated whole blood,apheresis plasma showed a higher FⅧ.Conclusion There is no significant quality difference between apheresis fresh frozen plasma and the fresh frozen plasma prepared by centrifugation of donated whole blood.The levels of coagulation factors in the former are even higher than those of the latter.

关 键 词：单采血浆 新鲜冰冻血浆 质量比较 

分 类 号：R457.14[医药卫生—治疗学]