尿毒症患者腹膜透析置管用导丝的临床研究  

Clinical study on filament for inserting peritoneal catheters in continuous ambulatory peritoneal dialysis

作　　者：金弢[1] 熊焰[1] 杨晓光[1] 

机构地区：[1]沈阳市红十字会医院肾内科,辽宁沈阳110013

出　　处：《国际泌尿系统杂志》2011年第6期733-736,共4页International Journal of Urology and Nephrology

基　　金：沈阳科学技术计划项目（1091162-9-00）

摘　　要：目的比较腹膜透析置管术用涂层金属导丝在临床使用上的作用和意义，以利于腹膜透析的开展。方法对行腹膜透析置管术的95例慢性肾功能衰竭尿毒症期的患者，根据其所使用的导丝类型不同，将病人分为普通导丝对照组（69例）和涂层导丝观察组（26例）两组，统计其腹膜炎发病率并进行比较。结果置管术后进行腹膜透析，两组患者发生腹膜炎的次数分别为18次和3次。其中，普通导丝对照组腹膜炎发病率为26．1％，涂层导丝观察组腹膜炎发病率为11．5％，两组比较有统计学差异；普通导丝对照组腹膜炎感染率（两次腹膜炎发作的间隔月）为31．89病人月，涂层导丝观察组的腹膜炎感染率为59．67病人月，两组比较也有统计学差异。结论在腹膜透析置管术中使用涂层导丝，避免了因铜丝表面脱落至腹腔ql发感染及重金属中毒的倾向，减少导管相关并发症及腹膜炎的发生，从而延长了患者的生存时间，降低病死率，并有助于降低患者的医疗成本，节约医疗资源。Objectives To study the possibility and significance of filament coated with a layer of TiN tor inserting peritoneal catheters in peritoneal dialysis （PD）. Methods 95 patients with chronic renal failure （CRF） were divided into two groups： 69 patients in original filament group and 26 patients in coated filament group. The peritonitis incidence of both groups is compared. Results The peI＇itonitis incidences are 26. 1% for the original filament group and 11.5 % for the coated filament group, respectively. The average durations between two neighbor peritonitis are 31.89 patient months for the original filament group and 59.67 patient months for the coated filament group. There are statistical significance between the two groups on both peritonitis incidence and the average duration. Conclusions It is promising to use the coated filament for inserting peritoneal catheters in peritoneal dialysis for preventing abdominal infection, deereasing peritonitis incidence, extending the life time, decreasing the fatality rate, decreasing medical treatment cost for patients, and saving medical resource.

关 键 词：尿毒症 腹膜透析 

分 类 号：R692.5[医药卫生—泌尿科学]