膈下逐瘀汤联合芬必得治疗气滞血瘀型原发性痛经的临床疗效  

Clinical effect of Gexiazhuyu decoction combined with Fenbid in treatment of primary dysmenorrhea

作　　者：王建霞[1] 姜静霞[1] 张蕾[1] 

机构地区：[1]江阴市中医院妇产科,江苏江阴214400

出　　处：《医药论坛杂志》2011年第19期73-76,共4页Journal of Medical Forum

摘　　要：目的探讨膈下逐瘀汤联合布洛芬缓释胶囊(芬必得)治疗气滞血瘀型原发性痛经的临床疗效及不良反应。方法选择气滞血瘀型原发性痛经患者90例,随机分为3组,各30例。联合治疗组口服膈下逐瘀汤联合芬必得,单纯西药组仅口服芬必得,单纯中药组仅口服膈下逐瘀汤,3组患者均在经潮前3d开始服用,连服5d,共观察3个月经周期,记录治疗前后疼痛积分情况,计算各组总有效率。结果联合治疗组治疗后疼痛积分均明显低于单纯西药组和单纯中药组,且单纯中药组明显低于单纯西药组;联合治疗组的总有效率(96.7%)明显高于单纯西药组(66.7%),但与单纯中药组(90.0%)比较无统计学差异,单纯中药组总有效率明显高于单纯西药组。结论中西药联合治疗原发性痛经的疗效优于单纯西药或单纯中药治疗。Objective To explore the clinical effect and adverse reactions of Gexiazhuyu Decoc- tion combined with ibuprofen sustained release capsules （Fenbid） in treatment of primary dysmenorrhea of qi stagnation and blood stasis. Methods Totally 90 cases of primary dysmenorrheal with the syn- drome type of qi stagnancy and blood stasis were randomly divided into 3 groups, each group with 30 cases. Patients in combined group were given Fenbid and Gexiazhuyu Decoction, which in western medicine（Fenbid） group were given only Fenbid, and in traditional Chinese medicine（TCM） group were only given Gexiazhuyu Decoction. All drugs were taken orally 3 days before menstruation, contin- ually 5 days, altogether 3 menstrual cycles. The accumulate points of pain before and after treatment were recorded, and the total effective rates were calculated. Results The accumulate points of pain in combined group were significantly lower than that in the other two groups, and which in TCM group were significantly lower than that in Fenbid group. The total effective rates in combined group were sig- nificantly higher than that in Fenbid group, and compared with TCM group, there was no statistics difference. The total effective rate in TCM group was higher than that in Fenbid group. Conclusions The clinical effect of TCM combined with western medicine on primary dysmenorrhea is better than simple TCM or simple western medicine.

关 键 词：布洛芬缓释胶囊 原发性痛经 联合治疗 

分 类 号：R271.113[医药卫生—中医妇科学]