糖尿病周围神经病变常见中医证型与相关指标的关系研究  

Relationship between Common TCM Syndromes of Diabetic Peripheral Neuropathy and Correlative Indicators

作　　者：张兰[1] 姜维娜[1] 

机构地区：[1]辽宁中医药大学附属医院,辽宁沈阳110032

出　　处：《中国中医药信息杂志》2011年第11期23-24,30,共3页Chinese Journal of Information on Traditional Chinese Medicine

基　　金：辽宁省高等学校优秀人才支持计划(2009R40)

摘　　要：目的探讨糖尿病周围神经病变(DPN)的中医证型分布规律,并回顾性研究DPN常见中医证型与相关指标的关系。方法收集近1年于辽宁中医药大学附属医院住院的DPN患者147例,分为气阴两虚、气虚血瘀、阴虚血瘀、阳虚血瘀、痰瘀阻络5种证型,分别记录患者年龄、体质指数(BMI)、糖尿病病程、糖化血红蛋白(HbA1c)、C反应蛋白(CRP)等指标,并分别进行相关性分析。结果收集的147例DPN患者中,阳虚血瘀证最为多见,但较其他证型差异无统计学意义(P>0.05)。阴虚血瘀证年龄最小,与其余证型比较差异有统计学意义(P<0.01,P<0.05)。痰瘀阻络证的病程明显高于气阴两虚证(P<0.05),BMI明显高于其余各证型(P<0.01,P<0.05)。阴虚血瘀证的HbA1c明显低于其余各证(P<0.05)。各证型间C反应蛋白差异无统计学意义。结论年龄偏小的DPN患者以阴虚血瘀为主要证型,其HbA1c较低。痰瘀阻络证糖尿病病程明显长于气阴两虚证,其BMI较高。Objective To explore the TCM syndromes distribution rule about diabetic peripheral neuropathy（DPN）,and to retrospectively study the relationship between common TCM syndromes of DPN and correlative indicators.Methods Total of 147 cases of inpatients with DPN from Affiliated Hospital of Liaoning University of Traditional Chinese Medicine in the recent year were divided into 5 syndromes：deficiency of both qi and yin,qi deficiency and blood stasis,yin deficiency and blood stasis,yang deficiency and blood stasis,phlegm and blood stasis.Their correlative indicators including age,BMI,course of diabetes,HbA1c,C-reactive protein（CRP） were recorded,and the correlationship was analyzed.Results The number of yang deficiency and blood stasis syndrome was the largest in the 147 cases of collected DPN patients,but there was no statistical significance compared with other syndromes（P0.05）.The patients of yin deficiency and blood stasis syndrome were the youngest,the differences were significant compared with other four syndromes（P0.01,P0.05）.It was obvious that the course of phlegm and blood stasis syndrome was longer than the course of qi and yin deficiency syndrome（P0.05）,and the level of BMI was higher than any other syndrome（P0.01,P0.05）.The level of HbA1c of yin asthenia and blood stasis syndrome was lower than any other syndrome（P0.05）.There were no significant differences in the level of CRP among different syndromes（P0.05）.Conclusion Yin deficiency and blood stasis syndrome is the main clinical TCM syndrome of younger DPN patients,and its level of HbA1c was lower.The course of diabetes of phlegm and blood stasis syndrome was longer than that of qi and yin deficiency syndrome,and its level of BMI was higher.

关 键 词：糖尿病周围神经病变 中医证型 年龄 糖化血红蛋白 体质指数 回顾性调查 

分 类 号：R259.872[医药卫生—中西医结合]