离子色谱法对丁二酸中微量甲酸和乙酸的检测  

Determination of Trace Formic and Acetic Acids in Succinic Acid

作　　者：段正康[1] 李立南[1] 马帅[1] 贺玉平[1] 

机构地区：[1]湘潭大学化工学院,湖南湘潭411105

出　　处：《湘潭大学自然科学学报》2011年第3期82-85,共4页Natural Science Journal of Xiangtan University

基　　金：化工过程模拟与优化教育部工程研究中心资助项目(2008HGZX03)

摘　　要：建立了测定丁二酸中微量甲酸和乙酸的离子色谱法(IC).最佳色谱分析条件为:IC-A1亲水性阴离子交换分离柱(5μm×4.6 mm×10 cm),淋洗液为0.8 mmol/L邻苯二甲酸,电导检测器,电导率0.1μS/cm,流速0.5 mL/min,柱温45℃.在上述色谱条件下,甲酸和乙酸的线性范围分别为0.02～500、0.05～500μg/L,线性相关系数均大于0.999 9.样品中甲酸、乙酸的加标回收率为98.96%～100.90%,其相对标准偏差(RSD)均小于1.5%.该方法具有操作简便、稳定、准确、可重复的特点,可用于由顺丁烯二酸酐催化加氢生产的丁二酸中微量甲酸和乙酸的定性定量分析.An ion chromatorgraphic（IC） method was developed for the determination of trace formic acid and acetic acid in succinic acid.The optimization of separation was performed on a IC-A1 hydrophilic ion exchange column（5 μm×4.6 mm×10 cm）.The solution containing 0.8 mmol/L phthalic acid was used as eluent at a flow rate of 0.5 mL/min and column temperature was set at 45 ℃.The conductivity detector was selected for detection and arranged at 0.1 μS/cm.Under the optimized conditions,the results showed that formic and acetic acids were separated well in the linear ranges of 0.02～500 μg/L and 0.05～500 μg/L,respectively,and the correlation coefficients of the two acids were all above 0.999 9.Recoveries of formic and acetic acids were all between 98.96% and 100.90% with relative standard deviations（RSDs） less than 1.5%.This method is simple,fast,stable,accurate and reproducible,and could be applied in the qualitative and quantitative analysis of trace formic and acetic acids in succinic acid compound manufactured by catalytic hydrogenation of maleic anhydride.

关 键 词：离子色谱 丁二酸 甲酸 乙酸 

分 类 号：O224[理学—运筹学与控制论]